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A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols

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Corre, Christophe, Haynes, Stuart W., Malet, Nicolas, Song, Lijiang and Challis, Gregory L.. (2011) A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols. Chemical Communications, Vol.46 (No.23). pp. 4079-4081. ISSN 1359-7345

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Abstract

The label from [3-C-13]-L-glycerol is incorporated into the hydroxymethyl group of methylenomycin furans suggesting a butenolide intermediate in their biosynthesis.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QR Microbiology
Divisions: Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH): Streptomyces coelicolor, Antibiotic-producing organisms, Streptomycin, Biosynthesis, Furans
Journal or Publication Title: Chemical Communications
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Official Date: 2011
Volume: Vol.46
Number: No.23
Number of Pages: 3
Page Range: pp. 4079-4081
Identification Number: 10.1039/c000496k
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Grant number: BB/E008003/1 (BBSRC)
References:

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URI: http://wrap.warwick.ac.uk/id/eprint/5788

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