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A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols

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Corre, Christophe, Haynes, Stuart W., Malet, Nicolas, Song, Lijiang and Challis, Gregory L. (2011) A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols. Chemical Communications, Vol.46 (No.23). pp. 4079-4081. doi:10.1039/c000496k ISSN 1359-7345.

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Official URL: http://dx.doi.org/10.1039/c000496k

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Abstract

The label from [3-C-13]-L-glycerol is incorporated into the hydroxymethyl group of methylenomycin furans suggesting a butenolide intermediate in their biosynthesis.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QR Microbiology
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
Library of Congress Subject Headings (LCSH): Streptomyces coelicolor, Antibiotic-producing organisms, Streptomycin, Biosynthesis, Furans
Journal or Publication Title: Chemical Communications
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Official Date: 2011
Dates:
DateEvent
2011Published
Volume: Vol.46
Number: No.23
Number of Pages: 3
Page Range: pp. 4079-4081
DOI: 10.1039/c000496k
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Grant number: BB/E008003/1 (BBSRC)

Data sourced from Thomson Reuters' Web of Knowledge

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