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A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols
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Corre, Christophe, Haynes, Stuart W., Malet, Nicolas, Song, Lijiang and Challis, Gregory L. (2011) A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols. Chemical Communications, Vol.46 (No.23). pp. 4079-4081. doi:10.1039/c000496k ISSN 1359-7345.
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Official URL: http://dx.doi.org/10.1039/c000496k
Abstract
The label from [3-C-13]-L-glycerol is incorporated into the hydroxymethyl group of methylenomycin furans suggesting a butenolide intermediate in their biosynthesis.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QR Microbiology |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
| Library of Congress Subject Headings (LCSH): | Streptomyces coelicolor, Antibiotic-producing organisms, Streptomycin, Biosynthesis, Furans | ||||
| Journal or Publication Title: | Chemical Communications | ||||
| Publisher: | Royal Society of Chemistry | ||||
| ISSN: | 1359-7345 | ||||
| Official Date: | 2011 | ||||
| Dates: |
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| Volume: | Vol.46 | ||||
| Number: | No.23 | ||||
| Number of Pages: | 3 | ||||
| Page Range: | pp. 4079-4081 | ||||
| DOI: | 10.1039/c000496k | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | ||||
| Grant number: | BB/E008003/1 (BBSRC) |
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