The Library
Photorhabdusand a host of hosts
Tools
Waterfield, Nicholas R., Ciche, Todd and Clarke, David (2009) Photorhabdusand a host of hosts. Annual Review of Microbiology, Volume 63 (Number 1). pp. 557-574. doi:10.1146/annurev.micro.091208.073507 ISSN 0066-4227.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1146/annurev.micro.091208.073...
Abstract
Photorhabdus is a member of the family Enterobacteriaceae that lives in a mutualistic association with a Heterorhabditis nematode worm. The nematode worm burrows into insect prey and regurgitates Photorhabdus, which goes on to kill the insect. The nematode feeds off the growing bacteria until the insect tissues are exhausted, whereupon they reassociate and leave the cadaver in search of new prey. This highly efficient partnership has been used for many years as a biological crop protection agent. The dual nature of Photorhabdus as a pathogen and mutualist makes it a superb model for understanding these apparently exclusive activities. Furthermore, recently identified clinical isolates of Photorhabdus are helping us to understand how human pathogens can emerge from the enormous reservoir of invertebrate pathogens in the environment. As Photorhabdus has never been found outside a host animal, its niche represents an entirely biotic landscape. In this review we discuss what molecular adaptations allow this bacterium to complete this fascinating and complex life cycle.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Journal or Publication Title: | Annual Review of Microbiology | ||||
Publisher: | Annual Reviews | ||||
ISSN: | 0066-4227 | ||||
Official Date: | 2009 | ||||
Dates: |
|
||||
Volume: | Volume 63 | ||||
Number: | Number 1 | ||||
Page Range: | pp. 557-574 | ||||
DOI: | 10.1146/annurev.micro.091208.073507 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |