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Plasma deposited metal Schiff-base compounds as antimicrobials

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Poulter, Neil, Donaldson, Matthew, Mulley, Geraldine, Duque, Luis, Waterfield, Nicholas R., Shard, Alex G., Spencer, Steve, Jenkins, A. Tobias A. and Johnson, Andrew L. (2011) Plasma deposited metal Schiff-base compounds as antimicrobials. New Journal of Chemistry, Volume 35 (Number 7). pp. 1477-1484. doi:10.1039/c1nj20091g

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Official URL: http://dx.doi.org/10.1039/C1NJ20091G

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Abstract

This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial efficacy of the two compounds were observed, suggesting possible mechanisms for antimicrobial activity. The ZSB system was plasma deposited under various pulse conditions onto non-woven fabric, and the antimicrobial efficacy of the resultant film measured for Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest the potential utility of this compound as an effective antimicrobial thin film, and confirm the critical role the ligands play in effecting antimicrobial activity.

Item Type: Journal Article
Divisions: Faculty of Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection
Faculty of Medicine > Warwick Medical School
Journal or Publication Title: New Journal of Chemistry
Publisher: Royal Society of Chemistry
ISSN: 1144-0546
Official Date: 2011
Dates:
DateEvent
2011Published
Volume: Volume 35
Number: Number 7
Page Range: pp. 1477-1484
DOI: 10.1039/c1nj20091g
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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