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Plasma deposited metal Schiff-base compounds as antimicrobials
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Poulter, Neil, Donaldson, Matthew, Mulley, Geraldine, Duque, Luis, Waterfield, Nicholas R., Shard, Alex G., Spencer, Steve, Jenkins, A. Tobias A. and Johnson, Andrew L. (2011) Plasma deposited metal Schiff-base compounds as antimicrobials. New Journal of Chemistry, Volume 35 (Number 7). pp. 1477-1484. doi:10.1039/c1nj20091g ISSN 1144-0546.
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Official URL: http://dx.doi.org/10.1039/C1NJ20091G
Abstract
This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial efficacy of the two compounds were observed, suggesting possible mechanisms for antimicrobial activity. The ZSB system was plasma deposited under various pulse conditions onto non-woven fabric, and the antimicrobial efficacy of the resultant film measured for Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest the potential utility of this compound as an effective antimicrobial thin film, and confirm the critical role the ligands play in effecting antimicrobial activity.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | New Journal of Chemistry | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 1144-0546 | ||||
Official Date: | 2011 | ||||
Dates: |
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Volume: | Volume 35 | ||||
Number: | Number 7 | ||||
Page Range: | pp. 1477-1484 | ||||
DOI: | 10.1039/c1nj20091g | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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