Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Tetrazine-norbornene cycloadditions in macromolecular synthesis and functionalisation

Tools
- Tools
+ Tools

Hansell, Claire F. (2013) Tetrazine-norbornene cycloadditions in macromolecular synthesis and functionalisation. PhD thesis, University of Warwick.

[img]
Preview
Text
WRAP_THESIS_Hansell_2013.pdf - Submitted Version

Download (22Mb) | Preview
Official URL: http://webcat.warwick.ac.uk/record=b2691430~S1

Request Changes to record.

Abstract

This thesis explores the use of the tetrazine–norbornene inverse electron demand Diels-Alder cycloaddition reaction in polymer and materials science. Chapter 1 gives an introduction to the main concepts and techniques used throughout the thesis. Chapter 2 applies the tetrazine–norbornene reaction to polymer endfunctionalisation and polymer–polymer coupling, in both organic media and water, and establishes the methods (UV/vis and 1H NMR spectroscopies) for monitoring the coupling reaction. Chapter 3 applies the reaction to the modification of a self-assembled polymer micelle and demonstrates its use in tandem with the coppercatalysed azide–alkyne click reaction. The synthesis of an amphiphile bearing both norbornene and alkyne groups is described, the amphiphile is self-assembled and a one-pot dual functionalisation of both the core and shell carried out. Chapter 4 describes the formation and analysis by a variety of methods of sub-20 nm sized polystyrene nanoparticles through the single chain collapse of a norbornene-decorated polymer, ligated with a bisfunctional tetrazine. Chapter 5 discusses attempts to further expand the use of the reaction of tetrazines to polymers bearing pendent alkene groups. The synthesis and characterisation of such polymers is detailed, and attempts to functionalise with a variety of tetrazines described.

Item Type: Thesis or Dissertation (PhD)
Subjects: Q Science > QD Chemistry
Library of Congress Subject Headings (LCSH): Macromolecules -- Synthesis, Pericyclic reactions, Diels-Alder reaction, Tetrazine
Official Date: 2013
Dates:
DateEvent
2013Submitted
Institution: University of Warwick
Theses Department: Department of Chemistry
Thesis Type: PhD
Publication Status: Unpublished
Supervisor(s)/Advisor: O'Reilly, Rachel K.
Sponsors: Warwick Postgraduate Research Scholarship (WPRS)
Extent: xxvi, 268 leaves : illustrations.
Language: eng

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us