Chan, Jacqueline, Sergeant, Martin J., Lee, Oona Y.-C., Minnikin, David E., Besra, Gurdyal S., Pap, Ilidkó, Spigelman, Mark, Donoghue, Helen D. and Pallen, Mark J. (2013) Metagenomic analysis of tuberculosis in a mummy. New England Journal Of Medicine , Volume 369 (Number3). pp. 289-290. doi:10.1056/NEJMc1302295

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Abstract

In 1994, a crypt containing 242 bodies was discovered in Vác, Hungary. Many of the bodies were naturally mummified, including the remains of Terézia Hausmann (referred to as Body 68 in the Supplementary Appendix, available with the full text of this letter at NEJM.org), who died on December 25, 1797, at 28 years of age.1,2 A chest radiograph of the remains was clear, but the cachectic appearance of the body was consistent with a diagnosis of tuberculosis. In a previous study, molecular analyses of a chest sample obtained from the body confirmed a diagnosis of tuberculosis and provided some limited genotypic data and quantitative information that suggested extremely good preservation of mycobacterial DNA.1,2

Item Type:	Journal Item
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title:	New England Journal Of Medicine
Publisher:	Massachusetts Medical Society
ISSN:	0028-4793
Official Date:	18 July 2013
Dates:	Date Event 18 July 2013 Published
Volume:	Volume 369
Number:	Number3
Page Range:	pp. 289-290
DOI:	10.1056/NEJMc1302295
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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