The Library
The expression profile of Escherichia coli K-12 in response to minimal, optimal and excess copper concentrations
Tools
Kershaw, C. J., Brown, Nigel L. , Constantinidou, Chrystala, Patel, Mala D. and Hobman, Jon L. (2005) The expression profile of Escherichia coli K-12 in response to minimal, optimal and excess copper concentrations. Microbiology, Volume 151 (Number 4). pp. 1187-1198. doi:10.1099/mic.0.27650-0 ISSN 1350-0872.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1099/mic.0.27650-0
Abstract
The gene expression profile of Escherichia coli K-12 MG1655 grown in minimal medium supplemented with elevated copper concentrations (as copper-glycine) has been analysed using whole-genome oligonucleotide microarrays. At 750 μM copper-glycine, the expression of both the cue and cus copper-export systems is evident. At near-lethal copper concentrations (2 mM copper-glycine), the expression of these two regulons increases significantly. Other regulons with increased transcription in response to elevated concentrations of copper-glycine include those for the superoxide stress response, iron homeostasis, and envelope stress. Furthermore, a variety of ORFs with decreased expression in response to increased copper-glycine has been identified, including the zinc ABC transporter and genes involved in the chemotactic response.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Journal or Publication Title: | Microbiology | ||||
Publisher: | Society for General Microbiology | ||||
ISSN: | 1350-0872 | ||||
Official Date: | April 2005 | ||||
Dates: |
|
||||
Volume: | Volume 151 | ||||
Number: | Number 4 | ||||
Page Range: | pp. 1187-1198 | ||||
DOI: | 10.1099/mic.0.27650-0 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |