The Library
High-throughput whole-genome sequencing to dissect the epidemiology of Acinetobacter baumannii isolates from a hospital outbreak
Tools
Lewis, T., Loman, Nicholas J., Bingle, L., Jumaa, P., Weinstock, G. M., Mortiboy, D. and Pallen, Mark J. (2010) High-throughput whole-genome sequencing to dissect the epidemiology of Acinetobacter baumannii isolates from a hospital outbreak. Journal of Hospital Infection, Volume 75 (Number 1). pp. 37-41. doi:10.1016/j.jhin.2010.01.012 ISSN 0195-6701.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.jhin.2010.01.012
Abstract
Shared care of military and civilian patients has resulted in transmission of multidrug-resistant Acinetobacter baumannii (MDR-Aci) from military casualties to civilians. Current typing technologies have been useful in revealing relationships between isolates of A. baumannii but they are unable to resolve differences between closely related isolates from small-scale outbreaks, where chains of transmission are often unclear. In a recent hospital outbreak in Birmingham, six patients were colonised with MDR-Aci isolates indistinguishable using standard techniques. We used whole-genome sequencing to identify single nucleotide polymorphisms in these isolates, allowing us to discriminate between alternative epidemiological hypotheses in this setting.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Journal or Publication Title: | Journal of Hospital Infection | ||||
Publisher: | W B Saunders Co Ltd. | ||||
ISSN: | 0195-6701 | ||||
Official Date: | 2010 | ||||
Dates: |
|
||||
Volume: | Volume 75 | ||||
Number: | Number 1 | ||||
Page Range: | pp. 37-41 | ||||
DOI: | 10.1016/j.jhin.2010.01.012 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |