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Analysis of plant materials for molecules of pharmaceutical importance
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Suberu, John O. (2013) Analysis of plant materials for molecules of pharmaceutical importance. PhD thesis, University of Warwick.
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WRAP_THESIS_Suberu_2013.pdf - Submitted Version - Requires a PDF viewer. Download (18Mb) | Preview |
Official URL: http://webcat.warwick.ac.uk/record=b2692649~S1
Abstract
Natural products are an important source for drug discovery. At present there is a resurgent interest in pharmacognosy as a platform for new combinations of active principles to provide highly potent and low-cost medications to treat a growing population with an increasing longevity. This product studied phytochemical interactions in Artemisia annua plant extracts using anti-plasmodium and anti-proliferation assays to identify interactions with potential therapeutic implications. To enable the study a rapid tandem quadrupole mass spectrometry (TQD) method was developed for metabolites in the plant and the validation indices showed the method to be robust, quick, sensitive and adequate for a range of applications [...]
Item Type: | Thesis (PhD) | ||||
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Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
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Library of Congress Subject Headings (LCSH): | Drug development, Pharmacognosy, Artemisia, Phytochemicals -- Molecular aspects, Pharmaceutical chemistry | ||||
Official Date: | July 2013 | ||||
Dates: |
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Institution: | University of Warwick | ||||
Theses Department: | School of Engineering | ||||
Thesis Type: | PhD | ||||
Publication Status: | Unpublished | ||||
Supervisor(s)/Advisor: | Lapkin, Alexei; Barker, Guy C.; Sullivan, Neil F., 1959- | ||||
Sponsors: | Engineering and Physical Sciences Research Council (EPSRC); SensaPharm Ltd. | ||||
Extent: | 1 volume (various pagings) : illustrations. | ||||
Language: | eng |
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