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Growth-phase-dependent expression of virulence factors in an M1T1 clinical isolate of streptococcus pyogenes
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Unnikrishnan, Meera, Cohen, Jonathan and Sriskandan, Shiranee (1999) Growth-phase-dependent expression of virulence factors in an M1T1 clinical isolate of streptococcus pyogenes. Infection and Immunity, Volume 67 (Number 10). pp. 5495-5499. ISSN 0019-9567.
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Official URL: http://iai.asm.org/content/67/10/5495.full
Abstract
The effect of growth phase on expression of virulence-associated factors was studied by Northern hybridization in an M1T1 clinical isolate of Streptococcus pyogenes. Expression of M protein, C5a peptidase, and capsule was maximal in the exponential phase of growth, while streptococcal pyrogenic exotoxins A and B and mitogenic factor were maximally expressed in later phases of growth.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QR Microbiology | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Streptococcus pyogenes, Virulence (Microbiology) | ||||
Journal or Publication Title: | Infection and Immunity | ||||
Publisher: | American Society for Microbiology | ||||
ISSN: | 0019-9567 | ||||
Official Date: | October 1999 | ||||
Dates: |
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Volume: | Volume 67 | ||||
Number: | Number 10 | ||||
Page Range: | pp. 5495-5499 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Medical Research Council (Great Britain) (MRC) |
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