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Acute and transient psychotic disorders : precursors, epidemiology, course and outcome
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Singh, Swaran P., Burns, Tom, Amin, Shazad, Jones, Peter B. and Harrison, Glynn (2004) Acute and transient psychotic disorders : precursors, epidemiology, course and outcome. The British Journal of Psychiatry, Volume 185 (Number 6). pp. 452-459. doi:10.1192/bjp.185.6.452 ISSN 0007-1250.
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Official URL: http://dx.doi.org/10.1192/bjp.185.6.452
Abstract
Background ICD–10 has introduced the diagnostic group acute and transient psychotic disorders (ATPDs; F23).
Aims To validate the nosological distinctiveness of ICD–10 ATPDs by following up an inception cohort with first-episode psychosis.
Method All patients with first-episode psychosis identified in Nottingham between 1992 and 1994 and diagnosed using ICD–10 criteria were reassessed 3 years later. ATPD outcomes were compared with schizophrenia and affective psychosis. Multivariate analyses were conducted to determine whether acute onset and early remission predicted favourable 3-year outcome in first-episode psychosis.
Results Of 168 cases of first-episode psychosis, 32 (19%) received an intake diagnosis of ATPD. The diagnosis of ATPD was stable in women over 3 years, but not in men. Outcomes in ATPD were better than in schizophrenia and similar to affective psychosis. In non-affective psychoses, favourable outcomes were a function of gender and premorbid functioning rather than acute onset and early remission.
Conclusions The ICD–10 criteria for ATPDs identify a diagnostically unstable group of disorders. Acute onset and early remission do not independently predict favourable outcome over 3 years in first-episode psychosis.
| Item Type: | Journal Article | ||||
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| Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry | ||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Psychoses -- Treatment, Psychoses -- Epidemiology, Mental illness -- Classification | ||||
| Journal or Publication Title: | The British Journal of Psychiatry | ||||
| Publisher: | Royal College of Psychiatrists | ||||
| ISSN: | 0007-1250 | ||||
| Official Date: | 2004 | ||||
| Dates: |
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| Volume: | Volume 185 | ||||
| Number: | Number 6 | ||||
| Page Range: | pp. 452-459 | ||||
| DOI: | 10.1192/bjp.185.6.452 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Version or Related Resource: | Conference abstract: Singh, S.P., et al. (2008). Acute and transient psychotic disorders: Precursors, epidemiology, course and outcome. European Psychiatry, 23(S2), pp. S147-S148. http://wrap.warwick.ac.uk/id/eprint/30122 | ||||
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