The Library
Asymmetric reduction of 2,2-dimethyl-6-(2-oxoalkyl/oxoaryl)-1,3-dioxin-4-ones and application to the synthesis of (+)-yashabushitriol
Tools
Fang, Zhijia (Researcher in chemistry), Clarkson, Guy J. and Wills, Martin (2013) Asymmetric reduction of 2,2-dimethyl-6-(2-oxoalkyl/oxoaryl)-1,3-dioxin-4-ones and application to the synthesis of (+)-yashabushitriol. Tetrahedron Letters, Volume 54 (Number 50). pp. 6834-6837. doi:10.1016/j.tetlet.2013.10.010 ISSN 0040-4039.
|
PDF
WRAP_9574780-ch-280915-tetl-d-13-02110_corrected_180913.pdf - Accepted Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. Download (1149Kb) | Preview |
Official URL: http://dx.doi.org/10.1016/j.tetlet.2013.10.010
Abstract
The asymmetric transfer hydrogenation of a series of 2,2-dimethyl-6-(2-oxoalkyl)-1,3-dioxin-4-ones and 2,2-dimethyl-6-(2-oxoaryl)-1,3-dioxin-4-ones was achieved in high enantiomeric excess using a Ru(II) catalyst. The aryl substrates were most compatible with the methodology and this process facilitated a total synthesis of enantiomerically pure (+)-yashabushitriol.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Library of Congress Subject Headings (LCSH): | Catalysis, Asymmetric synthesis, Reduction (Chemistry), Ketones, Hydrogenation, Ruthenium | ||||
Journal or Publication Title: | Tetrahedron Letters | ||||
Publisher: | Elsevier | ||||
ISSN: | 0040-4039 | ||||
Official Date: | 2013 | ||||
Dates: |
|
||||
Volume: | Volume 54 | ||||
Number: | Number 50 | ||||
Page Range: | pp. 6834-6837 | ||||
DOI: | 10.1016/j.tetlet.2013.10.010 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Date of first compliant deposit: | 23 November 2016 | ||||
Date of first compliant Open Access: | 23 November 2016 | ||||
Funder: | University of Warwick |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year