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Management of hyperphosphataemia in chronic kidney disease : summary of National Institute for Health and Clinical Excellence (NICE) Guideline
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Dasgupta, Indranil, Shroff, Rukshana, Bennett-Jones, David and McVeigh, Gary (2013) Management of hyperphosphataemia in chronic kidney disease : summary of National Institute for Health and Clinical Excellence (NICE) Guideline. Nephron Clinical Practice, Volume 124 (Number 1-2). pp. 1-9. doi:10.1159/000354711 ISSN 1660-2110.
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Official URL: http://dx.doi.org/10.1159/000354711
Abstract
Bone disease and ectopic calcification are the two main consequences of hyperphosphataemia of chronic kidney disease (CKD). Observational studies have demonstrated that hyperphosphataemia in CKD is associated with increased mortality. Furthermore, the use of phosphate binders in dialysis patients is associated with significantly lower mortality. The UK Renal Registry data show significant underachievement of phosphate targets in dialysis patients. It is believed to be due to wide variation in how management interventions are used. The National Institute for Health and Clinical Excellence (NICE) has developed a guideline on the management of hyperphosphataemia in CKD. This is based on the evidence currently available using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology. This review outlines the recommendations including research recommendations and discusses methodology, rationale and challenges faced in developing this guideline and the health economic model used to assess the cost-effectiveness of different phosphate binders. © 2013 S. Karger AG, Basel
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
| Journal or Publication Title: | Nephron Clinical Practice | ||||
| Publisher: | S. Karger AG | ||||
| ISSN: | 1660-2110 | ||||
| Official Date: | 2013 | ||||
| Dates: |
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| Volume: | Volume 124 | ||||
| Number: | Number 1-2 | ||||
| Page Range: | pp. 1-9 | ||||
| DOI: | 10.1159/000354711 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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