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Valuing the health states associated with Chlamydia trachomatis infections and their sequelae : a systematic review of economic evaluations and primary studies
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Jackson, Louise J., Auguste, Peter, Lowen, Nicola and Roberts, Tracy E. (2014) Valuing the health states associated with Chlamydia trachomatis infections and their sequelae : a systematic review of economic evaluations and primary studies. Value in Health, Volume 17 (Number 1). pp. 116-130. doi:10.1016/j.jval.2013.10.005 ISSN 1098-3015.
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Official URL: http://dx.doi.org/10.1016/j.jval.2013.10.005
Abstract
Objectives: Economic evaluations of interventions to prevent and control sexually transmitted infections such as Chlamydia trachomatis are increasingly required to present their outcomes in terms of quality-adjusted life-years using preference-based measurements of relevant health states. The objectives of this study were to critically evaluate how published cost-effectiveness studies have conceptualized and valued health states associated with chlamydia and to examine the primary evidence available to inform health state utility values (HSUVs).
Methods: A systematic review was conducted, with searches of six electronic databases up to December 2012. Data on study characteristics, methods, and main results were extracted by using a standard template.
Results: Nineteen economic evaluations of relevant interventions were included. Individual studies considered different health states and assigned different values and durations. Eleven studies cited the same source for HSUVs. Only five primary studies valued relevant health states. The methods and viewpoints adopted varied, and different values for health states were generated.
Conclusions: Limitations in the information available about HSUVs associated with chlamydia and its complications have implications for the robustness of economic evaluations in this area. None of the primary studies could be used without reservation to inform cost-effectiveness analyses in the United Kingdom. Future debate should consider appropriate methods for valuing health states for infectious diseases, because recommended approaches may not be suitable. Unless we adequately tackle the challenges associated with measuring and valuing health-related quality of life for patients with chlamydia and other infectious diseases, evaluating the cost-effectiveness of interventions in this area will remain problematic.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Value in Health | ||||
Publisher: | Elsevier Inc. | ||||
ISSN: | 1098-3015 | ||||
Official Date: | January 2014 | ||||
Dates: |
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Volume: | Volume 17 | ||||
Number: | Number 1 | ||||
Page Range: | pp. 116-130 | ||||
DOI: | 10.1016/j.jval.2013.10.005 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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