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Obesity as an independent predictor of outcome after endovascular abdominal aortic aneurysm repair
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Saratzis, Athanasios, Saedon, Mahmud H., Melas, Nikolaos, Kitas, George D. and Mahmood, Asif (2014) Obesity as an independent predictor of outcome after endovascular abdominal aortic aneurysm repair. Annals of Vascular Surgery, Volume 28 (Number 4). pp. 816-822. doi:10.1016/j.avsg.2013.07.008 ISSN 0890-5096.
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Official URL: http://dx.doi.org/10.1016/j.avsg.2013.07.008
Abstract
Background
Obesity is increasingly common in patients referred for the management of an abdominal aortic aneurysm (AAA). Evidence of the effect of obesity on outcomes after endovascular repair (EVAR) is not well established. We sought to compare the immediate and midterm outcomes of elective EVAR between obese and nonobese patients in a case control study.
Methods
Patients undergoing elective EVAR were divided in 2 groups: obese (defined as a body mass index [BMI] ≥30 kg/m2) and nonobese (mean BMI [kg/m2] ± SD: 33 ± 1 vs 25 ± 3). Both groups were case-matched for age, sex, smoking, and AAA diameter. One hundred fifty-nine patients were included (mean age: 69 ± 9 years; 10 women [9%]; mean BMI: 28 ± 5 kg/m2; 53 were obese and 106 were nonobese). All aneurysms were successfully excluded. Mean follow-up was 34 ± 13 months.
Results
All patients who developed a complication within the perioperative period (≤30 days) were obese (P = 0.01). Thirteen patients (8.2%) died during follow-up (8 obese versus 5 nonobese; P = 0.76). Survival and non–procedure-related morbidity did not differ significantly between the obese and nonobese groups (P = 0.64 and 0.16; log-rank test). BMI was not associated with mortality or non–procedure-related morbidity on multivariate analysis (mortality—hazard ratio: 1.0 [95% confidence interval: 0.9–1.2]; P = 0.37; non–procedure-related morbidity—hazard ratio: 1.0 [95% confidence interval: 0.9–1.1], P = 0.2).
Conclusions
This is the first case control study to assess the independent impact of obesity in the outcome after EVAR. No difference was documented with regards to mortality or non–aneurysm-related morbidity.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Annals of Vascular Surgery | ||||
| Publisher: | Elsevier | ||||
| ISSN: | 0890-5096 | ||||
| Official Date: | May 2014 | ||||
| Dates: |
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| Volume: | Volume 28 | ||||
| Number: | Number 4 | ||||
| Page Range: | pp. 816-822 | ||||
| DOI: | 10.1016/j.avsg.2013.07.008 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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