Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

The use of supplementary immunisation activities to improve uptake of current and future vaccines in low-income and middle-income countries : a systematic review protocol

Tools
- Tools
+ Tools

Kagina, B. M., Wiysonge, C. S., Machingaidze, S., Abdullahi, L. H., Adebayo, E., Uthman, Olalekan A. and Hussey, Gregory D. (2014) The use of supplementary immunisation activities to improve uptake of current and future vaccines in low-income and middle-income countries : a systematic review protocol. BMJ Open, Volume 4 (Number 2). Article number e004429. doi:10.1136/bmjopen-2013-004429

[img]
Preview
PDF
WRAP_Uthman_e004429.full.pdf - Published Version - Requires a PDF viewer.
Available under License Creative Commons Attribution Non-commercial.

Download (593Kb) | Preview
Official URL: http://dx.doi.org/10.1136/bmjopen-2013-004429

Request Changes to record.

Abstract

Introduction: Immunisation coverage data in low-income and middle-income countries (LMICs) suggest that more strategies need to be implemented to achieve and sustain optimal vaccine uptake. Among possible strategies to improve immunisation coverage are supplementary immunisation activities (SIAs). We are therefore interested in conducting a systematic review to assess whether SIAs complement routine immunisation programmes to improve vaccination coverage and prevent disease outbreaks.

Methods: Our systematic review will focus on studies conducted in LMICs. With the help of an information specialist, we will search for eligible studies in PubMed, Web of Science, Scopus, Africa-Wide, Cochrane Library, WHOLIS, CINAHL, PDQ-Evidence as well as reference lists of relevant publications. Additionally, we will contact relevant organisations such as WHO and GAVI. Two authors will independently extract data from eligible studies and independently assess risk of bias by assessing the adequacy of study characteristics. The primary meta-analysis will use random effects models due to expected interstudies heterogeneity. Dichotomous data will be analysed using relative risk and continuous data using weighted mean differences (or standardised mean differences), both with 95% CIs.

Discussion: The findings from this systematic review will be discussed in the context of strengthening routine childhood immunisation services, routine adolescent immunisation services and introduction of future vaccines against tuberculosis and HIV/AIDS.

Study strengths: Unbiased selection of many studies conducted in different settings. This will strengthen the validity of the review results.

Study limitations: Heterogeneity of the study settings of the low-income, lower-middle-income and upper-middle-income countries as well as heterogeneity in study designs.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Immunization -- Developing countries, Developing countries -- Health aspects
Journal or Publication Title: BMJ Open
Publisher: BMJ
ISSN: 2044-6055
Official Date: 21 January 2014
Dates:
DateEvent
21 January 2014Accepted
Volume: Volume 4
Number: Number 2
Article Number: Article number e004429
DOI: 10.1136/bmjopen-2013-004429
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
Funder: Aeras Global TB Vaccine Foundation

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics

twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us