Interaction based functional clustering of genomic data
Krishna, Ritesh, Li, Chang-Tsun and Buchanan-Wollaston, Vicky (2009) Interaction based functional clustering of genomic data. In: 9th IEEE International Conference on BioInformatics and BioEngineering, Taichung, Taiwan, 22-24 June 2009. Published in: 2009 9th IEEE International Conference on Bioinformatics and Bioengineering pp. 130-137.Full text not available from this repository.
Official URL: http://dx.doi.org/10.1109/BIBE.2009.28
We present the first report on Granger causality based detection of functional modules from temporal gene expression data. The approach uses temporal causal relationships shared between pair of genes to derive a connection matrix, which is further analyzed using graph-theoretic techniques. The approach is evaluated against a synthesized dataset and a real biological dataset obtained for Arabidopsis thaliana. We show the effectiveness of our approach by analyzing the results using the existing biological literature.
|Item Type:||Conference Item (Paper)|
|Divisions:||Faculty of Science > Computer Science|
|Journal or Publication Title:||2009 9th IEEE International Conference on Bioinformatics and Bioengineering|
|Number of Pages:||8|
|Page Range:||pp. 130-137|
|Access rights to Published version:||Restricted or Subscription Access|
|Conference Paper Type:||Paper|
|Title of Event:||9th IEEE International Conference on BioInformatics and BioEngineering|
|Type of Event:||Conference|
|Location of Event:||Taichung, Taiwan|
|Date(s) of Event:||22-24 June 2009|
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