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Interaction based functional clustering of genomic data
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Krishna, Ritesh, Li, Chang-Tsun and Buchanan-Wollaston, Vicky (2009) Interaction based functional clustering of genomic data. In: 9th IEEE International Conference on BioInformatics and BioEngineering, Taichung, Taiwan, 22-24 June 2009. Published in: 2009 9th IEEE International Conference on Bioinformatics and Bioengineering pp. 130-137. ISBN 978-1-4244-4294-2. doi:10.1109/BIBE.2009.28
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Official URL: http://dx.doi.org/10.1109/BIBE.2009.28
Abstract
We present the first report on Granger causality based detection of functional modules from temporal gene expression data. The approach uses temporal causal relationships shared between pair of genes to derive a connection matrix, which is further analyzed using graph-theoretic techniques. The approach is evaluated against a synthesized dataset and a real biological dataset obtained for Arabidopsis thaliana. We show the effectiveness of our approach by analyzing the results using the existing biological literature.
Item Type: | Conference Item (Paper) | ||||
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Subjects: | R Medicine | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Computer Science | ||||
Journal or Publication Title: | 2009 9th IEEE International Conference on Bioinformatics and Bioengineering | ||||
Publisher: | IEEE | ||||
ISBN: | 978-1-4244-4294-2 | ||||
Official Date: | 2009 | ||||
Dates: |
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Number of Pages: | 8 | ||||
Page Range: | pp. 130-137 | ||||
DOI: | 10.1109/BIBE.2009.28 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Conference Paper Type: | Paper | ||||
Title of Event: | 9th IEEE International Conference on BioInformatics and BioEngineering | ||||
Type of Event: | Conference | ||||
Location of Event: | Taichung, Taiwan | ||||
Date(s) of Event: | 22-24 June 2009 |
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