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A critical literature review of health economic evaluations of rotavirus vaccination
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Aballéa, Samuel, Millier, Aurélie, Quilici, Sibilia, Caroll, Stuart, Petrou, Stavros and Toumi, Mondher (2013) A critical literature review of health economic evaluations of rotavirus vaccination. Human vaccines & immunotherapeutics, Volume 9 (Number 6). pp. 1272-1288. doi:10.4161/hv.24253 ISSN 2164-5515.
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Official URL: http://dx.doi.org/10.4161/hv.24253
Abstract
Two licensed vaccines are available to prevent RVGE in infants. A worldwide critical review of economic evaluations of these vaccines was conducted. The objective was to describe differences in methodologies, assumptions and inputs and determine the key factors driving differences in conclusions. 68 economic evaluations were reviewed. RV vaccination was found to be cost-effective in developing countries, while conclusions varied between studies in developed countries. Many studies found that vaccination was likely to be costeffective under some scenarios, such as lower prices scenarios, inclusion of herd protection, and/or adoption of a societal perspective. Other reasons for variability included uncertainty around healthcare visits incidence and lack of consensus on quality of life (QoL) valuation for infants and caregivers. New evidence on the vaccination effectiveness in real-world, new ways of modeling herd protection and assessments of QoL in children could help more precisely define the conditions under which RV vaccination would be cost-effective in developed countries.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Human vaccines & immunotherapeutics | ||||
Publisher: | Landes Bioscience | ||||
ISSN: | 2164-5515 | ||||
Official Date: | June 2013 | ||||
Dates: |
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Volume: | Volume 9 | ||||
Number: | Number 6 | ||||
Page Range: | pp. 1272-1288 | ||||
DOI: | 10.4161/hv.24253 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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