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Construction of DNA–polymer hybrids using intercalation interactions
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Wilks, Thomas R., Pitto-Barry, Anaïs, Kirby, Nigel, Stulz, Eugen and O'Reilly, Rachel K. (2014) Construction of DNA–polymer hybrids using intercalation interactions. Chemical Communications, Volume 50 (Number 11). pp. 1338-1340. doi:10.1039/c3cc48726a ISSN 1359-7345.
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Official URL: http://dx.doi.org/10.1039/C3CC48726A
Abstract
Reversible addition–fragmentation chain transfer (RAFT) polymerisation was used to produce a range of polymers terminated with an acridine group, which intercalates efficiently into dsDNA; the structure of the polymer determines the nature and strength of the interaction. Using a short 63 base pair dsDNA, discrete and well-defined DNA–polymer hybrid nanoparticles were formed, which were characterised by dynamic light scattering, small-angle X-ray scattering and atomic force microscopy.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Journal or Publication Title: | Chemical Communications | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 2014 | ||||
Dates: |
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Volume: | Volume 50 | ||||
Number: | Number 11 | ||||
Page Range: | pp. 1338-1340 | ||||
DOI: | 10.1039/c3cc48726a | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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