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Outcome assessment after hip fracture : is EQ-5D the answer?
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Parsons, Nicholas R., Griffin, Xavier L., Achten, Juul and Costa, Matthew L. (2014) Outcome assessment after hip fracture : is EQ-5D the answer? Bone and Joint Research, Volume 3 (Number 3). pp. 69-75. doi:10.1302/2046-3758.33.2000250 ISSN 2046-3758.
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Official URL: http://dx.doi.org/10.1302/2046-3758.33.2000250
Abstract
Objectives: To study the measurement properties of a joint specific patient reported outcome measure, a measure of capability and a general health-related quality of life (HRQOL) tool in a large cohort of patients with a hip fracture.
Methods: Responsiveness and associations between the Oxford Hip Score (a hip specific measure: OHS), ICEpop CAPability (a measure of capability in older people: ICECAP-O) and EuroQol EQ-5D (general health-related quality of life measure: EQ-5D) were assessed using data available from two large prospective studies. The three outcome measures were assessed concurrently at a number of fixed follow-up time-points in a consecutive sequence of patients, allowing direct assessment of change from baseline, inter-measure associations and validity using a range of statistical methods.
Results: ICECAP-O was not responsive to change. EQ-5D was responsive to change from baseline, with an estimated standardised effect size for the two datasets of 0.676 and 0.644 at six weeks and four weeks respectively; this was almost as responsive to change as OHS (1.14 at four weeks). EQ-5D correlated strongly with OHS; Pearson correlation coefficients were 0.74, 0.77 and 0.70 at baseline, four weeks and four months. EQ-5D is a moderately good predictor of death at 12 months following hip fracture. Furthermore, EQ-5D reported by proxies (relatives and carers) behaves similarly to self-reported scores.
Conclusions: Our findings suggest that a general HRQOL tool such as EQ-5D could be used to measure outcome for patients recovering from hip fracture, including those with cognitive impairment.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > R Medicine (General) | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit |
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| Library of Congress Subject Headings (LCSH): | Hip joint -- Wounds and injuries, Outcome assessment (Medical care) | ||||||||
| Journal or Publication Title: | Bone and Joint Research | ||||||||
| Publisher: | British Editorial Society of Bone and Joint Surgery | ||||||||
| ISSN: | 2046-3758 | ||||||||
| Official Date: | March 2014 | ||||||||
| Dates: |
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| Volume: | Volume 3 | ||||||||
| Number: | Number 3 | ||||||||
| Page Range: | pp. 69-75 | ||||||||
| DOI: | 10.1302/2046-3758.33.2000250 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 28 July 2016 | ||||||||
| Date of first compliant Open Access: | 28 July 2016 | ||||||||
| Funder: | National Institute for Health Research (Great Britain) (NIHR) | ||||||||
| Grant number: | RP-DG-1210-10022 (NIHR) |
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