Bryson, K., Luck, Michael (Michael M.), Joy, Mike and Jones, David T. (2000) Applying agents to bioinformatics in GeneWeaver. In: Klusch, Matthias, 1965- and Kerschberg, Larry, (eds.) Cooperative information agents IV : The future of information agents in cyberspace. Lecture Notes in Computer Science (Volume 1860). Berlin ; London: Springer, pp. 60-71. ISBN 9783540677031

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Abstract

Recent years have seen dramatic and sustained growth in the amount of genomic data being generated, including in late 1999 the first complete sequence of a human chromosome. The challenge now faced by biological scientists is to make sense of this vast amount of accumulated and accumulating data. Fortunately, numerous databases are provided as resources containing relevant data, and there are similarly many available programs that analyse this data and attempt to understand it. However, the key problem in analysing this genomic data is how to integrate the software and primary databases in a flexible and robust way. The wide range of available programs conform to very different input, output and processing requirements, typically with little consideration given to issues of integration, and in many cases with only token efforts made in the direction of usability. In this paper, we introduce the problem domain and describe GeneWeaver, a multi-agent system for genome analysis. We explain the suitability of the information agent paradigm to the problem domain, focus on the problem of incorporating different existing analysis tools, and describe progress to date.

Item Type:	Book Item
Subjects:	Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software
Divisions:	Faculty of Science > Computer Science
Library of Congress Subject Headings (LCSH):	Artificial intelligence, Database management, Information storage and retrieval systems
Series Name:	Lecture Notes in Computer Science
Publisher:	Springer
Place of Publication:	Berlin ; London
ISBN:	9783540677031
Book Title:	Cooperative information agents IV : The future of information agents in cyberspace
Editor:	Klusch, Matthias, 1965- and Kerschberg, Larry
Official Date:	2000
Dates:	Date Event 2000 Published
Number:	Volume 1860
Page Range:	pp. 60-71
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Engineering and Physical Sciences Research Council (EPSRC), Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)

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