Monnier, Annabelle, Liverani, Silvia, Bouvet, Regis, Jesson, Beline, Smith, J. Q., 1953-, Mosser, Jean, Corellou, Florence and Bouget, Francois-Yves. (2010) Orchestrated transcription of biological processes in the marine picoeukaryote ostreococcus exposed to light/dark cycles. BMC Genomics, Vol.11 . Article no. 192. ISSN 1471-2164

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Abstract

Background: Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species of Ostreococcus and Micromonas has led to the emergence of picophytoplankton comparative genomics. Sequencing has revealed many unexpected features about genome structure and led to several hypotheses on Ostreococcus biology and physiology. Despite the accumulation of genomic data, little is known about gene expression in eukaryotic picophytoplankton. Results: We have conducted a genome-wide analysis of gene expression in Ostreococcus tauri cells exposed to light/dark cycles (L/D). A Bayesian Fourier Clustering method was implemented to cluster rhythmic genes according to their expression waveform. In a single L/D condition nearly all expressed genes displayed rhythmic patterns of expression. Clusters of genes were associated with the main biological processes such as transcription in the nucleus and the organelles, photosynthesis, DNA replication and mitosis. Conclusions: Light/Dark time-dependent transcription of the genes involved in the main steps leading to protein synthesis (transcription basic machinery, ribosome biogenesis, translation and aminoacid synthesis) was observed, to an unprecedented extent in eukaryotes, suggesting a major input of transcriptional regulations in Ostreococcus. We propose that the diurnal co-regulation of genes involved in photoprotection, defence against oxidative stress and DNA repair might be an efficient mechanism, which protects cells against photo-damage thereby, contributing to the ability of O. tauri to grow under a wide range of light intensities.

Item Type:	Journal Article
Subjects:	T Technology > TP Chemical technology Q Science > QH Natural history > QH426 Genetics
Divisions:	Faculty of Science > Statistics
Journal or Publication Title:	BMC Genomics
Publisher:	BioMed Central Ltd.
ISSN:	1471-2164
Date:	22 March 2010
Volume:	Vol.11
Number of Pages:	13
Page Range:	Article no. 192
Identification Number:	10.1186/1471-2164-11-192
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Funder:	European Network of Excellence, ANR Biosys, Conseil Regional de Bretagne
URI:	http://wrap.warwick.ac.uk/id/eprint/6120

Data sourced from Thomson Reuters' Web of Knowledge

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