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Electrospray ionisation source incorporating electrodynamic ion focusing and conveying
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Colburn, Alex W., Barrow, Mark P., Gill, M. S., Giannakopulos, Anastassios E. and Derrick, Peter J. (2008) Electrospray ionisation source incorporating electrodynamic ion focusing and conveying. In: 7th International Conference on Charged Particle Optics (CPO-7), Trinity Coll, Cambridge, England, Jul 24-28, 2006. Published in: Physics Procedia-Proceedings of the Seventh International Conference on Charged Particle Optics , Vol.1 (No.1). pp. 51-60. doi:10.1016/j.phpro.2008.07.077 ISSN 1875-3892.
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Official URL: http://dx.doi.org/10.1016/j.phpro.2008.07.077
Abstract
The control and transmission of charged entities in the intermediate to high pressure regime is of primary importance in areas such as atmospheric pressure ionisation. In an electrospray ionisation source where small apertures separate differentially pumped vacuum regions in the inlet systems to mass spectrometers, a large proportion of the available ion current is lost to the surrounding electrode structures. A new electrospray ionisation source, incorporating electrodynamic focusing and conveying of charged entities in two vacuum regions is described. The new source design incorporates ion accumulation and pulsed extraction to allow application in techniques such as Fourier Transform Ion Cyclotron Resonance and orthogonal time-of-flight where a pulsed ion source in required. The design of the new source is described and preliminary experimental results using an orthogonal time-of-flight configuration are presented. (C) 2008 Elsevier B.V. All rights reserved.
| Item Type: | Conference Item (UNSPECIFIED) | ||||
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| Subjects: | Q Science > QC Physics Q Science > QD Chemistry |
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| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
| Library of Congress Subject Headings (LCSH): | Electrospray ionization mass spectrometry, Mass spectrometers, Ion sources, Electrodynamics | ||||
| Series Name: | Physics Procedia | ||||
| Journal or Publication Title: | Physics Procedia-Proceedings of the Seventh International Conference on Charged Particle Optics | ||||
| Publisher: | Elsevier BV | ||||
| ISSN: | 1875-3892 | ||||
| Editor: | Munro, E and Rouse, J | ||||
| Official Date: | 2008 | ||||
| Dates: |
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| Volume: | Vol.1 | ||||
| Number: | No.1 | ||||
| Number of Pages: | 10 | ||||
| Page Range: | pp. 51-60 | ||||
| DOI: | 10.1016/j.phpro.2008.07.077 | ||||
| Status: | Not Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Title of Event: | 7th International Conference on Charged Particle Optics (CPO-7) | ||||
| Type of Event: | Conference | ||||
| Location of Event: | Trinity Coll, Cambridge, England | ||||
| Date(s) of Event: | Jul 24-28, 2006 |
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