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Electrospray ionisation source incorporating electrodynamic ion focusing and conveying

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Colburn, Alex W., Barrow, Mark P., Gill, M. S., Giannakopulos, Anastassios E. and Derrick, Peter J. (2008) Electrospray ionisation source incorporating electrodynamic ion focusing and conveying. In: 7th International Conference on Charged Particle Optics (CPO-7), Trinity Coll, Cambridge, England, Jul 24-28, 2006. Published in: Physics Procedia-Proceedings of the Seventh International Conference on Charged Particle Optics , Vol.1 (No.1). pp. 51-60.

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Abstract

The control and transmission of charged entities in the intermediate to high pressure regime is of primary importance in areas such as atmospheric pressure ionisation. In an electrospray ionisation source where small apertures separate differentially pumped vacuum regions in the inlet systems to mass spectrometers, a large proportion of the available ion current is lost to the surrounding electrode structures. A new electrospray ionisation source, incorporating electrodynamic focusing and conveying of charged entities in two vacuum regions is described. The new source design incorporates ion accumulation and pulsed extraction to allow application in techniques such as Fourier Transform Ion Cyclotron Resonance and orthogonal time-of-flight where a pulsed ion source in required. The design of the new source is described and preliminary experimental results using an orthogonal time-of-flight configuration are presented. (C) 2008 Elsevier B.V. All rights reserved.

Item Type: Conference Item (UNSPECIFIED)
Subjects: Q Science > QC Physics
Q Science > QD Chemistry
Divisions: Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH): Electrospray ionization mass spectrometry, Mass spectrometers, Ion sources, Electrodynamics
Series Name: Physics Procedia
Journal or Publication Title: Physics Procedia-Proceedings of the Seventh International Conference on Charged Particle Optics
Publisher: Elsevier BV
ISSN: 1875-3892
Editor: Munro, E and Rouse, J
Official Date: 2008
Volume: Vol.1
Number: No.1
Number of Pages: 10
Page Range: pp. 51-60
Identification Number: 10.1016/j.phpro.2008.07.077
Status: Not Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Title of Event: 7th International Conference on Charged Particle Optics (CPO-7)
Type of Event: Conference
Location of Event: Trinity Coll, Cambridge, England
Date(s) of Event: Jul 24-28, 2006
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URI: http://wrap.warwick.ac.uk/id/eprint/6205

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