The Library
Divide and ProsPer : the emerging role of PtdIns3P in cytokinesis
Tools
Nezis, I. P., Sagona, Antonia P., Schink, Kay Oliver and Stenmark, H. (Harald) (2010) Divide and ProsPer : the emerging role of PtdIns3P in cytokinesis. Trends in Cell Biology, Volume 20 (Number 11). pp. 642-649. doi:10.1016/j.tcb.2010.08.010 ISSN 0962-8924.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.tcb.2010.08.010
Abstract
Cytokinesis is the final step of cell division whereby the dividing cells separate physically. Failure of this process has been proposed to cause tumourigenesis. Several specific lipids are essential for cytokinesis, and recent evidence has revealed that phosphatidylinositol 3-phosphate (PtdIns3P) — a well-known regulator of endosomal trafficking, receptor signaling, nutrient sensing and autophagy — plays an evolutionarily conserved role during cytokinesis. The emerging picture is that PtdIns3P and its regulators and effectors constitute a novel regulatory mechanism for cytokinesis. Elucidating the role of PtdIns3P in cytokinesis might contribute to insight into mechanisms of tumour development and suppression.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||
Journal or Publication Title: | Trends in Cell Biology | ||||
Publisher: | Elsevier Ltd. | ||||
ISSN: | 0962-8924 | ||||
Official Date: | November 2010 | ||||
Dates: |
|
||||
Volume: | Volume 20 | ||||
Number: | Number 11 | ||||
Page Range: | pp. 642-649 | ||||
DOI: | 10.1016/j.tcb.2010.08.010 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |