Polin, Marco, Tuval, I., Drescher, K., Gollub, J. P. and Goldstein, R. E. (2009) Chlamydomonas swims with two "gears" in a eukaryotic version of run-and-tumble locomotion. Science, Volume 325 (Number 5939). pp. 487-490. doi:10.1126/science.1172667

Research output not available from this repository, contact author.

Request Changes to record.

Abstract

The coordination of eukaryotic flagella is essential for many of the most basic processes of life (motility, sensing, and development), yet its emergence and regulation and its connection to locomotion are poorly understood. Previous studies show that the unicellular alga Chlamydomonas, widely regarded as an ideal system in which to study flagellar biology, swims forward by the synchronous action of its two flagella. Using high-speed imaging over long intervals, we found a richer behavior: A cell swimming in the dark stochastically switches between synchronous and asynchronous flagellar beating. Three-dimensional tracking shows that these regimes lead, respectively, to nearly straight swimming and to abrupt large reorientations, which yield a eukaryotic version of the "run-and-tumble" motion of peritrichously flagellated bacteria.

Item Type:	Journal Article
Divisions:	Faculty of Science > Physics
Journal or Publication Title:	Science
Publisher:	American Association for the Advancement of Science
ISSN:	0036-8075
Official Date:	24 July 2009
Dates:	Date Event 24 July 2009 Published
Volume:	Volume 325
Number:	Number 5939
Page Range:	pp. 487-490
DOI:	10.1126/science.1172667
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

Request changes or add full text files to a record

Repository staff actions (login required)

View Item