The Library
Binning metagenomic contigs by coverage and composition
Tools
Alneberg, Johannes, Bjarnason, Brynjar Smári, de Bruijn, Ino, Schirmer, Melanie, Quick, Joshua, Ijaz, Umer Z., Lahti, Leo, Loman, Nicholas J., Andersson, Anders F. and Quince, Christopher (2014) Binning metagenomic contigs by coverage and composition. Nature Methods, Volume 11 . pp. 1144-1146. doi:10.1038/nmeth.3103 ISSN 1548-7091.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1038/nmeth.3103
Abstract
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but because assembly does not reconstruct entire genomes, it is necessary to bin genome fragments. Here we present CONCOCT, a new algorithm that combines sequence composition and coverage across multiple samples, to automatically cluster contigs into genomes. We demonstrate high recall and precision on artificial as well as real human gut metagenome data sets.
Item Type: | Journal Article | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Microbiology & Infection Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||||||
Journal or Publication Title: | Nature Methods | ||||||||||
Publisher: | Nature Publishing Group | ||||||||||
ISSN: | 1548-7091 | ||||||||||
Official Date: | 2014 | ||||||||||
Dates: |
|
||||||||||
Volume: | Volume 11 | ||||||||||
Page Range: | pp. 1144-1146 | ||||||||||
DOI: | 10.1038/nmeth.3103 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published | ||||||||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |