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Assessment of copper corrosion from frameless copper IUDs after long-term in utero residence
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Wildemeersch, Dirk, Sabbe, Pieter-Jan, Dowsett, M. G., Flexer, Victoria, Thompson, Paul, Walker, David, Thomas, Pam A. and Adriaens, Annemie (2014) Assessment of copper corrosion from frameless copper IUDs after long-term in utero residence. Contraception, Volume 90 (Number 4). pp. 454-459. doi:10.1016/j.contraception.2014.05.009 ISSN 0010-7824.
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Official URL: http://dx.doi.org/10.1016/j.contraception.2014.05....
Abstract
Objective
To assess the site-specific corrosive behavior of the frameless intrauterine device (IUD) following long-term exposure to the uterine environment.
Study design
A qualitative and morphological study using X-ray diffraction (XRD) and scanning electron microscopy (SEM).
Results
Three GyneFix® IUDs that were in site up to 150 months were examined. In utero corroded copper sleeves were divided into 10 different groups based on their shape (U or O), orientation (inside or outside) and in utero residence time. XRD indicated the presence of solely cuprite (Cu2O) as corrosion product on both the inside and the outside of the copper sleeves, regardless of their shape. These results were confirmed by backscattered electron micrographs recorded on the inside, the outside and the cross-section of the IUD sleeve. SEM results suggest that shape and orientation slightly affect the corrosion rate.
Conclusion
The apparent copper loss from both sides of GyneFix copper tubes proves that both sides are a potential copper source and therefore justifies the design of GyneFix IUD. This could be beneficial for women as the IUD could be reduced in size and therefore better tolerated. The impact on bleeding could also be minimized.
Implication statement
Release of copper ions from both sides of the copper tubes of the frameless GyneFix® IUD allows the IUD to be reduced in size, contributing to better toleration. The impact on menstrual bleeding is also minimized by a smaller size of the foreign body.
Item Type: | Journal Article | ||||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Physics | ||||||||
Journal or Publication Title: | Contraception | ||||||||
Publisher: | Elsevier Inc. | ||||||||
ISSN: | 0010-7824 | ||||||||
Official Date: | 23 May 2014 | ||||||||
Dates: |
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Volume: | Volume 90 | ||||||||
Number: | Number 4 | ||||||||
Page Range: | pp. 454-459 | ||||||||
DOI: | 10.1016/j.contraception.2014.05.009 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access |
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