Ntoukakis, Vardis, Saur, Isabel M. L., Conlan, Brendon and Rathjen, John P. (2014) The changing of the guard : the Pto/Prf receptor complex of tomato and pathogen recognition. Current Opinion in Plant Biology, Volume 20 . pp. 69-74. doi:10.1016/j.pbi.2014.04.002 ISSN 1369-5266.

Research output not available from this repository.

Request-a-Copy directly from author or use local Library Get it For Me service.

Request Changes to record.

Abstract

One important model for disease resistance is the Prf recognition complex of tomato, which responds to different bacterial effectors. Prf incorporates a protein kinase called Pto as its recognition domain that mimics effector virulence targets, and activates resistance after interaction with specific effectors. Recent findings show that this complex is oligomeric, and reveal how this impacts mechanism. Oligomerisation brings two or more kinases into proximity, where they can phosphorylate each other after effector perception. Effector attack on one kinase activates another in trans, constituting a molecular trap for the effector. Oligomerisation of plant resistance proteins may be a general concept that broadens pathogen recognition and restricts the ability of pathogens to evolve virulence.

Item Type:	Journal Article
Divisions:	Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Journal or Publication Title:	Current Opinion in Plant Biology
Publisher:	Elsevier Ltd.
ISSN:	1369-5266
Official Date:	August 2014
Dates:	Date Event August 2014 Published 20 May 2014 Available
Volume:	Volume 20
Page Range:	pp. 69-74
DOI:	10.1016/j.pbi.2014.04.002
Status:	Peer Reviewed
Publication Status:	Published

Request changes or add full text files to a record

Repository staff actions (login required)

View Item