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Generalised stochastic model for characterisation of subcutaneous glucose time series
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Khovanova, N. A., Zhang, Yan and Holt, Tim A. (2014) Generalised stochastic model for characterisation of subcutaneous glucose time series. In: 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), Valencia, Spain, 1-4 Jun 2014. Published in: 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) pp. 484-487. doi:10.1109/BHI.2014.6864408
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Official URL: http://dx.doi.org/10.1109/BHI.2014.6864408
Abstract
A generalised stochastic model with second order differential equations is proposed to describe the response of blood glucose concentration to meals in groups of nondiabetic people and two types of diabetic patients. A variational Bayesian approach is applied in order to infer parameters of the models, and the best model was selected based on the computed log-evidence for each prandial event. The model with a linear structure represents most of the events, while the nonlinear terms need to be included more frequently for Type II diabetic patients. This indicates different physiological mechanisms of glucose absorption for different groups. The deterministic parameters and intensities of stochastic components are compared by groups using the ANOVA test, and the results show significant differences between the groups. This model can potentially be used for long term prediction of the glucose concentration response to external stimuli.
Item Type: | Conference Item (Paper) | ||||
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Subjects: | R Medicine > RB Pathology | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||
Library of Congress Subject Headings (LCSH): | Blood sugar monitoring, Blood -- Analysis | ||||
Journal or Publication Title: | 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) | ||||
Publisher: | Institute of Electrical and Electronics Engineers | ||||
Official Date: | 2014 | ||||
Dates: |
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Page Range: | pp. 484-487 | ||||
DOI: | 10.1109/BHI.2014.6864408 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Date of first compliant deposit: | 28 December 2015 | ||||
Date of first compliant Open Access: | 28 December 2015 | ||||
Conference Paper Type: | Paper | ||||
Title of Event: | 2014 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI) | ||||
Type of Event: | Conference | ||||
Location of Event: | Valencia, Spain | ||||
Date(s) of Event: | 1-4 Jun 2014 |
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