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Six challenges in the eradication of infectious diseases

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Klepac, Petra, Funk, S., Hollingsworth, T. Déirdre, Metcalf, C. J. E. and Hampson, Katie Ruth (2015) Six challenges in the eradication of infectious diseases. Epidemics, Volume 10 . pp. 97-101. doi:10.1016/j.epidem.2014.12.001 ISSN 1755-4365.

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Official URL: http://dx.doi.org/10.1016/j.epidem.2014.12.001

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Abstract

Eradication and elimination are increasingly a part of the global health agenda. Once control measures have driven infection to low levels, the ecology of disease may change posing challenges for eradication efforts. These challenges vary from identifying pockets of susceptibles, improving monitoring during and after the endgame, to quantifying the economics of disease eradication versus sustained control, all of which are shaped and influenced by processes of loss of immunity, susceptible build-up, emergence of resistance, population heterogeneities and non-compliance with control measures. Here we discuss how modelling can be used to address these challenges.

Item Type: Journal Article
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions: Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- )
Faculty of Science, Engineering and Medicine > Science > Mathematics
Library of Congress Subject Headings (LCSH): Communicable diseases -- Prevention
Journal or Publication Title: Epidemics
Publisher: Elsevier BV
ISSN: 1755-4365
Official Date: March 2015
Dates:
DateEvent
March 2015Published
12 December 2014Available
4 December 2014Accepted
3 December 2014Modified
3 March 2014Submitted
Volume: Volume 10
Number of Pages: 5
Page Range: pp. 97-101
DOI: 10.1016/j.epidem.2014.12.001
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 28 December 2015
Date of first compliant Open Access: 28 December 2015
Funder: AXA Group. Research Fund, Medical Research Council (Great Britain) (MRC), Bill & Melinda Gates Foundation, National Institutes of Health (U.S.) (NIH), Wellcome Trust (London, England)
Grant number: MR/K021680/1 (MRC),

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