UNSPECIFIED (2005) Role of apoptosis and cytokines in influenza virus morbidity. FEMS MICROBIOLOGY REVIEWS, 29 (4). pp. 837-850. ISSN 0168-6445

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Abstract

Influenza virus is a major human pathogen that causes epidemics and pandemics with increased morbidity and, especially in the elderly and those with pre-existing medical conditions, increased mortality. Influenza is characterised by respiratory symptoms and constitutional symptoms. Whilst knowledge of the mechanisms underlying host and tissue specificity has advanced considerably of late we still know relatively little about other aspects of influenza virus virulence. In this review, we will explore what is known about the role of apoptosis in respiratory epithelial cell damage and the role of cytokines in inflammation and constitutional symptoms with particular emphasis on the link between apoptosis, inflammation, fever and cytokine production. (c) 2004 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

Item Type:	Journal Item
Subjects:	Q Science > QR Microbiology
Journal or Publication Title:	FEMS MICROBIOLOGY REVIEWS
Publisher:	ELSEVIER SCIENCE BV
ISSN:	0168-6445
Date:	September 2005
Volume:	29
Number:	4
Number of Pages:	14
Page Range:	pp. 837-850
Identification Number:	10.1016/j.femsre.2004.12.003
Publication Status:	Published
URI:	http://wrap.warwick.ac.uk/id/eprint/6665

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