The Library
Functional imaging in adult and paediatric brain tumours
Tools
Tools
Tools
Peet, Andrew C., Arvanitis, Theodoros N., Leach, Martin O. and Waldman, Adam D. (2012) Functional imaging in adult and paediatric brain tumours. Nature Reviews Clinical Oncology, Volume 9 (Number 12). pp. 700-711. doi:10.1038/nrclinonc.2012.187
Research output not available from this repository, contact author.
Official URL: http://dx.doi.org/10.1038/nrclinonc.2012.187
Abstract
Imaging is a key component in the management of brain tumours, with MRI being the preferred modality for most clinical scenarios. However, although conventional MRI provides mainly structural information, such as tumour size and location, it leaves many important clinical questions, such as tumour type, aggressiveness and prognosis, unanswered. An increasing number of studies have shown that additional information can be obtained using functional imaging methods (which probe tissue properties), and that these techniques can give key information of clinical importance. These techniques include diffusion imaging, which can assess tissue structure, and perfusion imaging and magnetic resonance spectroscopy, which measures tissue metabolite profiles. Tumour metabolism can also be investigated using PET, with 18F-deoxyglucose being the most readily available tracer. This Review discusses these methods and the studies that have investigated their clinical use. A strong emphasis is placed on the measurement of quantitative parameters, which is a move away from the qualitative nature of conventional radiological reporting and presents major challenges, particularly for multicentre studies.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science > WMG (Formerly the Warwick Manufacturing Group) | ||||
| Journal or Publication Title: | Nature Reviews Clinical Oncology | ||||
| Publisher: | Nature Publishing Group | ||||
| ISSN: | 1759-4774 | ||||
| Official Date: | December 2012 | ||||
| Dates: |
|
||||
| Volume: | Volume 9 | ||||
| Number: | Number 12 | ||||
| Page Range: | pp. 700-711 | ||||
| DOI: | 10.1038/nrclinonc.2012.187 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
 |
View Item |
