Albon, E., Tsourapas, A., Frew, E., Davenport, C., Oyebode, F., Bayliss, S., Arvanitis, Theodoros N. and Meads, C. (2008) Structural neuroimaging in psychosis : a systematic review and economic evaluation. Health Technology Assessment, Volume 12 (Number 18).

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Abstract

The evidence to date suggests that if screening with structural neuroimaging was implemented in all patients presenting with psychotic symptoms, little would be found to affect clinical management in addition to that suspected by a full clinical history and neurological examination. From an economic perspective, the outcome is not clear. The strategy of neuroimaging for all is either cost-incurring or cost-saving (dependent upon whether MRI or CT is used) if the prevalence of organic causes is around 1%. However, these values are nested within a number of assumptions, and so have to be interpreted with caution. The main research priorities are to monitor the current use of structural neuroimaging in psychosis in the NHS to identify clinical triggers to its current use and subsequent outcomes; to undertake well-conducted diagnostic before-and-after studies on representative populations to determine the clinical utility of structural neuroimaging in this patient group, and to determine whether the most appropriate structural imaging modality in psychosis should be CT or MRI.

Item Type:	Journal Article
Divisions:	Faculty of Science > Psychology
Journal or Publication Title:	Health Technology Assessment
Publisher:	NIHR Health Technology Assessment programme
ISSN:	1366-5278
Official Date:	2008
Dates:	Date Event 2008 Published
Volume:	Volume 12
Number:	Number 18
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access

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