The Library
Factors associated with arthrogenous muscle inhibition in patellofemoral osteoarthritis
Tools
Callaghan, M. J., Parkes, M. J., Hutchinson, Charles E. and Felson, D. T. (2014) Factors associated with arthrogenous muscle inhibition in patellofemoral osteoarthritis. Osteoarthritis and Cartilage, Volume 22 (Number 6). pp. 742-746. doi:10.1016/j.joca.2014.03.015 ISSN 1063-4584.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.joca.2014.03.015
Abstract
Objectives
Arthrogenous muscle inhibition (AMI) is thought to contribute to quadriceps weakness in knee osteoarthritis (OA), but its relationship with structural changes of bone marrow lesions (BMLs), capsular distension and pain is unclear. This study's objective was to investigate the factors associated with AMI in subjects with symptomatic patellofemoral joint OA (PFJOA).
Design
126 Subjects with predominant PFJOA were assessed for pain by the visual analogue scale (VAS) for a nominated aggravating activity. Their more symptomatic knee underwent a magnetic resonance imaging (MRI) scan which was used to assess BMLs and synovitis which were scored using the Whole Organ MRI score (WORMS). Quadriceps AMI was measured by calculating the activation deficit and quadriceps strength assessed by isometric maximum voluntary contraction. Multiple linear regressions were used to assess factors associated with AMI.
Results
We studied 124 subjects [mean age 55.5 (SD 7.5); 57.14% female]. In regression analyses, higher levels of AMI were significantly associated with more severe knee pain and with lower BML score.
Conclusion
Quadriceps AMI in knee OA is associated with severity of knee pain and surprisingly with lower BML scores.
Item Type: | Journal Article | ||||||||
---|---|---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||||
Journal or Publication Title: | Osteoarthritis and Cartilage | ||||||||
Publisher: | Elsevier Science BV | ||||||||
ISSN: | 1063-4584 | ||||||||
Official Date: | 29 March 2014 | ||||||||
Dates: |
|
||||||||
Volume: | Volume 22 | ||||||||
Number: | Number 6 | ||||||||
Page Range: | pp. 742-746 | ||||||||
DOI: | 10.1016/j.joca.2014.03.015 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |