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Bladder cancer : ESMO Practice Guidelines for diagnosis, treatment and follow-up
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Bellmunt, Joaquim, Orsola, A., Leow, J. J., Wiegel, Thomas, De Santis, Maria and Horwich, Alan (2014) Bladder cancer : ESMO Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology, Volume 25 (Supplement 3). iii40-iii48. doi:10.1093/annonc/mdu223 ISSN 0923-7534.
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Official URL: http://dx.doi.org/10.1093/annonc/mdu223
Abstract
n Europe, an estimated 151 297 new cases of bladder cancer were diagnosed in 2012, with an age-standardised incidence rate (per 100 000 persons) of 17.7 for males and 3.5 for females. Overall, the annual crude incidence rate is 20.4/100 000. In 2012, there were 52 395 deaths from bladder cancer with an annual crude mortality rate of 7.1/100 000 [1]. Approximately 70% of patients with bladder cancer are >65 years of age.
The most common presenting symptom is painless haematuria, seen in >80% of patients. Others may also present with irritative symptoms such as dysuria, frequency or urgency. Symptoms of metastases such as bone or flank pain are rare. Most diagnosed cases of muscle-invasive bladder cancer (MIBC; 80%–90%) present as primary invasive bladder cancer. However, up to 15% of patients have a history of non-muscle-invasive bladder cancer (NMIBC), mainly high-risk cases.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Cancer Research Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Annals of Oncology | ||||
| Publisher: | Oxford University Press | ||||
| ISSN: | 0923-7534 | ||||
| Official Date: | 5 August 2014 | ||||
| Dates: |
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| Volume: | Volume 25 | ||||
| Number: | Supplement 3 | ||||
| Page Range: | iii40-iii48 | ||||
| DOI: | 10.1093/annonc/mdu223 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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