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Implementing newer agents for the management of castrate-resistant prostate cancer : what is known and what is needed?
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Mottet, Nicolas, Clarke, Noel W., De Santis, Maria , Zattoni, Filiberto, Morote, Juan and Joniau, Steven (2014) Implementing newer agents for the management of castrate-resistant prostate cancer : what is known and what is needed? BJU International, Volume 115 (Number 3). pp. 364-372. doi:10.1111/bju.12736 ISSN 1464-1603.
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Official URL: http://dx.doi.org/10.1111/bju.12736
Abstract
Men receiving androgen-deprivation therapy will in time develop metastatic castrate-resistant prostate cancer (mCRPC). Whilst effective treatment options for mCRPC have traditionally been limited, new agents are becoming available. Since 2010, the number and class of agents available to treat mCRPC has increased dramatically. As such, there is a need for clear guidance on the optimum treatment and sequence of treatments for mCRPC before and after chemotherapy. This evidence-based statement, reflecting the views of the authors, provides suggestions on the continued relevance of conventional approaches to first- and second-line treatment in mCRPC, the potential role of novel treatments, and factors that may influence the choice of hormonal agents and/or chemotherapy.
Item Type: | Journal Article | ||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Cancer Research Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | BJU International | ||||||
Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||
ISSN: | 1464-1603 | ||||||
Official Date: | 14 March 2014 | ||||||
Dates: |
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Volume: | Volume 115 | ||||||
Number: | Number 3 | ||||||
Page Range: | pp. 364-372 | ||||||
DOI: | 10.1111/bju.12736 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access |
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