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Short term heart rate variability to predict blood pressure drops due to standing : a pilot study
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Sannino, Giovanna, Melillo, Paolo, De Pietro, Giuseppe, Stranges, Saverio and Pecchia, Leandro (2015) Short term heart rate variability to predict blood pressure drops due to standing : a pilot study. BMC Medical Informatics and Decision Making, 15 (Supplement 3). S2. doi:10.1186/1472-6947-15-S3-S2 ISSN 1472-6947.
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Official URL: http://doi.org/10.1186/1472-6947-15-S3-S2
Abstract
Background
Standing from a bed or chair may cause a significant lowering of blood pressure (ΔBP), which may have severe consequences such as, for example, falls in older subjects. The goal of this study was to develop a mathematical model to predict the ΔBP due to standing in healthy subjects, based on their Heart Rate Variability, recorded in the 5 minutes before standing.
Methods
Heart Rate Variability was extracted from an electrocardiogram, recorded from 10 healthy subjects during the 5 minutes before standing. The blood pressure value was measured before and after rising. A mathematical model aiming to predict ΔBP based on Heart Rate Variability measurements was developed using a robust multi-linear regression and was validated with the leave-one-subject-out cross-validation technique.
Results
The model predicted correctly the ΔBP in 80% of experiments, with an error below the measurement error of sphygmomanometer digital devices (±4.5 mmHg), a false negative rate of 7.5% and a false positive rate of 10%. The magnitude of the ΔBP was associated with a depressed and less chaotic Heart Rate Variability pattern.
Conclusions
The present study showes that blood pressure lowering due to standing can be predicted by monitoring the Heart Rate Variability in the 5 minutes before standing.
Item Type: | Journal Article | ||||||
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Subjects: | R Medicine > RC Internal medicine | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||||
Library of Congress Subject Headings (LCSH): | Blood pressure, Heart beat | ||||||
Journal or Publication Title: | BMC Medical Informatics and Decision Making | ||||||
Publisher: | BioMed Central Ltd. | ||||||
ISSN: | 1472-6947 | ||||||
Official Date: | 11 September 2015 | ||||||
Dates: |
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Volume: | 15 | ||||||
Number: | Supplement 3 | ||||||
Article Number: | S2 | ||||||
DOI: | 10.1186/1472-6947-15-S3-S2 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access |
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