The Library
Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography
Tools
Foadi, James, Aller, Pierre, Alguel, Yilmaz, Cameron, Alexander, Axford, Danny, Owen, Robin L., Armour, Wes, Waterman, David G., Iwata, So and Evans, Gwyndaf (2013) Clustering procedures for the optimal selection of data sets from multiple crystals in macromolecular crystallography. Acta Crystallographica Section D Biological Crystallography, 69 (8). pp. 1617-1632. doi:10.1107/S0907444913012274 ISSN 0907-4449.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1107/S0907444913012274
Abstract
The availability of intense microbeam macromolecular crystallography beamlines at third-generation synchrotron sources has enabled data collection and structure solution from microcrystals of <10 µm in size. The increased likelihood of severe radiation damage where microcrystals or particularly sensitive crystals are used forces crystallographers to acquire large numbers of data sets from many crystals of the same protein structure. The associated analysis and merging of multi-crystal data is currently a manual and time-consuming step. Here, a computer program, BLEND, that has been written to assist with and automate many of the steps in this process is described. It is demonstrated how BLEND has successfully been used in the solution of a novel membrane protein.
Item Type: | Journal Article | ||||||||
---|---|---|---|---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||
Library of Congress Subject Headings (LCSH): | Crystallography -- Computer programs | ||||||||
Journal or Publication Title: | Acta Crystallographica Section D Biological Crystallography | ||||||||
Publisher: | Wiley-Blackwell Publishing, Inc. | ||||||||
ISSN: | 0907-4449 | ||||||||
Official Date: | August 2013 | ||||||||
Dates: |
|
||||||||
Volume: | 69 | ||||||||
Number: | 8 | ||||||||
Number of Pages: | 16 | ||||||||
Page Range: | pp. 1617-1632 | ||||||||
DOI: | 10.1107/S0907444913012274 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Open Access (Creative Commons) |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |