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Magnetic induction spectroscopy : non-contact measurement of the electrical conductivity spectra of biological samples

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Barai, Anup, Watson, S., Griffiths, H. and Patz, R. (2012) Magnetic induction spectroscopy : non-contact measurement of the electrical conductivity spectra of biological samples. Measurement Science & Technology, Volume 23 (Number 8). doi:10.1088/0957-0233/23/8/085501 ISSN 0957-0233.

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Official URL: http://dx.doi.org/10.1088/0957-0233/23/8/085501

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Abstract

Measurement of the electrical conductivity of biological tissues as a function of frequency, often termed 'bioelectrical impedance spectroscopy (BIS)', provides valuable information on tissue structure and composition. In implementing BIS though, there can be significant practical difficulties arising from the electrode–sample interface which have likely limited its deployment in industrial applications. In magnetic induction spectroscopy (MIS) these difficulties are eliminated through the use of fully non-contacting inductive coupling between the sensors and sample. However, inductive coupling introduces its own set of technical difficulties, primarily related to the small magnitudes of the induced currents and their proportionality with frequency. This paper describes the design of a practical MIS system incorporating new, highly-phase-stable electronics and compares its performance with that of electrode-based BIS in measurements on biological samples including yeast suspensions in saline (concentration 50–400 g l−1) and solid samples of potato, cucumber, tomato, banana and porcine liver. The shapes of the MIS spectra were in good agreement with those for electrode-based BIS, with a residual maximum discrepancy of 28%. The measurement precision of the MIS was 0.05 S m−1 at 200 kHz, improving to 0.01 S m−1 at a frequency of 20 MHz, for a sample volume of 80 ml. The data-acquisition time for each MIS measurement was 52 s. Given the value of spectroscopic conductivity information and the many advantages of obtaining these data in a non-contacting manner, even through electrically-insulating packaging materials if necessary, it is concluded that MIS is a technique with considerable potential for monitoring bio-industrial processes and product quality.

Item Type: Journal Article
Subjects: Q Science > QC Physics
Q Science > QD Chemistry
Q Science > QP Physiology
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions: Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group)
Library of Congress Subject Headings (LCSH): Impedance, Bioelectric, Impedance (Electricity), Spectrum analysis, Magnetic induction
Journal or Publication Title: Measurement Science & Technology
Publisher: Institute of Physics Publishing Ltd.
ISSN: 0957-0233
Official Date: 25 June 2012
Dates:
DateEvent
25 June 2012Published
18 January 2012Accepted
Volume: Volume 23
Number: Number 8
DOI: 10.1088/0957-0233/23/8/085501
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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