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Magnetic induction spectroscopy : non-contact measurement of the electrical conductivity spectra of biological samples
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Barai, Anup, Watson, S., Griffiths, H. and Patz, R. (2012) Magnetic induction spectroscopy : non-contact measurement of the electrical conductivity spectra of biological samples. Measurement Science & Technology, Volume 23 (Number 8). doi:10.1088/0957-0233/23/8/085501
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Official URL: http://dx.doi.org/10.1088/0957-0233/23/8/085501
Abstract
Measurement of the electrical conductivity of biological tissues as a function of frequency, often termed 'bioelectrical impedance spectroscopy (BIS)', provides valuable information on tissue structure and composition. In implementing BIS though, there can be significant practical difficulties arising from the electrode–sample interface which have likely limited its deployment in industrial applications. In magnetic induction spectroscopy (MIS) these difficulties are eliminated through the use of fully non-contacting inductive coupling between the sensors and sample. However, inductive coupling introduces its own set of technical difficulties, primarily related to the small magnitudes of the induced currents and their proportionality with frequency. This paper describes the design of a practical MIS system incorporating new, highly-phase-stable electronics and compares its performance with that of electrode-based BIS in measurements on biological samples including yeast suspensions in saline (concentration 50–400 g l−1) and solid samples of potato, cucumber, tomato, banana and porcine liver. The shapes of the MIS spectra were in good agreement with those for electrode-based BIS, with a residual maximum discrepancy of 28%. The measurement precision of the MIS was 0.05 S m−1 at 200 kHz, improving to 0.01 S m−1 at a frequency of 20 MHz, for a sample volume of 80 ml. The data-acquisition time for each MIS measurement was 52 s. Given the value of spectroscopic conductivity information and the many advantages of obtaining these data in a non-contacting manner, even through electrically-insulating packaging materials if necessary, it is concluded that MIS is a technique with considerable potential for monitoring bio-industrial processes and product quality.
| Item Type: | Journal Article | ||||||
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| Subjects: | Q Science > QC Physics Q Science > QD Chemistry Q Science > QP Physiology T Technology > TK Electrical engineering. Electronics Nuclear engineering |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group) | ||||||
| Library of Congress Subject Headings (LCSH): | Impedance, Bioelectric, Impedance (Electricity), Spectrum analysis, Magnetic induction | ||||||
| Journal or Publication Title: | Measurement Science & Technology | ||||||
| Publisher: | Institute of Physics Publishing Ltd. | ||||||
| ISSN: | 0957-0233 | ||||||
| Official Date: | 25 June 2012 | ||||||
| Dates: |
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| Volume: | Volume 23 | ||||||
| Number: | Number 8 | ||||||
| DOI: | 10.1088/0957-0233/23/8/085501 | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
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