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Prostate radiotherapy for men with metastatic disease : a new comparison in the systemic therapy in advancing or metastatic prostate cancer : evaluation of drug efficacy (STAMPEDE) trial

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Parker, Christopher C., Sydes, Matthew R., Mason, Malcolm D., Clarke, Noel W., Aebersold, Daniel, De Bono, Johann S., Dearnaley, David P., Ritchie, A. W. S., Russell, J. Martin, Thalmann, George, Parmar, Mahesh K. B. and James, Nicholas D. (2013) Prostate radiotherapy for men with metastatic disease : a new comparison in the systemic therapy in advancing or metastatic prostate cancer : evaluation of drug efficacy (STAMPEDE) trial. BJU International, 111 (5). pp. 697-699. doi:10.1111/bju.12087

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Official URL: http://dx.doi.org/10.1111/bju.12087

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Abstract

Many patients presenting with metastatic prostate cancerask whether they should have treatment to the prostateitself in addition to their hormone therapy. This question isincreasingly common and there is a growing sense thatthese inquiring patients may be on to something, asinternational randomised controlled trials have now provena survival benefit to adding radiotherapy (RT) to hormonetherapy for men with locally advanced disease [1,2]. Fromearly in 2013, the Systemic Therapy in Advancing orMetastatic Prostate Cancer: Evaluation of Drug Efficacy(STAMPEDE) trial will investigate whether treatmentdirec ted against the primary tumour might indeed retardmetastatic progression and thereby prolong survival bytesting the role of RT-to-the-prostate in men presentingwith metastatic disease

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences > Cancer Research Unit
Library of Congress Subject Headings (LCSH): Prostate -- Cancer, Metastasis
Journal or Publication Title: BJU International
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 1464-1603
Official Date: May 2013
Dates:
DateEvent
May 2013Published
12 April 2013Available
22 January 2013Accepted
9 January 2013Submitted
Volume: 111
Number: 5
Number of Pages: 3
Page Range: pp. 697-699
DOI: 10.1111/bju.12087
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Medical Research Council (Great Britain) (MRC), Cancer Research UK (CRUK), Novartis (Firm), Pfizer Ltd., Sanofi Aventis (Firm), Janssen Pharmaceutical Ltd., National Cancer Research Institute (NCRI)
Grant number: CRUK/06/019 (CRUK)

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