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Real-time growth rate for general stochastic SIR epidemics on unclustered networks
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Pellis, Lorenzo, Spencer, Simon E. F. and House, Thomas A. (2015) Real-time growth rate for general stochastic SIR epidemics on unclustered networks. Mathematical Biosciences, 265 . pp. 65-81. doi:10.1016/j.mbs.2015.04.006
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Official URL: http://dx.doi.org/10.1016/j.mbs.2015.04.006
Abstract
Networks have become an important tool for infectious disease epidemiology. Most previous theoretical studies of transmission network models have either considered simple Markovian dynamics at the individual level, or have focused on the invasion threshold and final outcome of the epidemic. Here, we provide a general theory for early real-time behaviour of epidemics on large configuration model networks (i.e. static and locally unclustered), in particular focusing on the computation of the Malthusian parameter that describes the early exponential epidemic growth. Analytical, numerical and Monte-Carlo methods under a wide variety of Markovian and non-Markovian assumptions about the infectivity profile are presented. Numerous examples provide explicit quantification of the impact of the network structure on the temporal dynamics of the spread of infection and provide a benchmark for validating results of large scale simulations
| Item Type: | Journal Article | ||||||||||
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| Subjects: | Q Science > QA Mathematics | ||||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Statistics | ||||||||||
| Library of Congress Subject Headings (LCSH): | Epidemiology -- Mathematical models, Epidemiology -- Statistical methods, Stochastic analysis, Branching processes | ||||||||||
| Journal or Publication Title: | Mathematical Biosciences | ||||||||||
| Publisher: | Elsevier Science Inc. | ||||||||||
| ISSN: | 0025-5564 | ||||||||||
| Official Date: | June 2015 | ||||||||||
| Dates: |
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| Volume: | 265 | ||||||||||
| Page Range: | pp. 65-81 | ||||||||||
| DOI: | 10.1016/j.mbs.2015.04.006 | ||||||||||
| Status: | Peer Reviewed | ||||||||||
| Publication Status: | Published | ||||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||||
| Funder: | Engineering and Physical Sciences Research Council (EPSRC) |
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