Hemming, Karla, Hutton, Jane, Glinianaia, S. V., Jarvis, S. N. and Platt, M. J. (2006) Differences between European birthweight standards: impact on classification of ‘small for gestational age’. Developmental Medicine and Child Neurology, Vol.48 (No.11). pp. 906-912. doi:10.1017/S0012162206001988 ISSN 0012-1622.

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Abstract

We describe a quantitative and comparative review of a selection of European birthweight standards for gestational age for singletons, to enable appropriate choices to be made for clinical and research use. Differences between median values at term across standards in 10 regions and misclassification of ‘small for gestational age’ (SGA), were studied. Sex and parity differences, exclusion criteria, and methods of construction were considered. There was wide variation between countries in exclusion criteria, methods of calculating standards, and median birthweight at term. The lightest standards (e.g. France's medians are 255g lower than Norway's medians) were associated with fewer exclusion criteria. Up to 20% of the population used in the construction of the Scottish standard would be classified as SGA using the Norwegian standard. Substantial misclassification of SGA is possible. Assumptions about variation used in the construction of some standards were not justified. It is not possible to conclude that there are real differences in birthweight standards between European countries. Country-based standards control for some population features but add misclassification due to the differing ways in which standards are derived. Standards should be chosen to reflect clinical or research need. If standards stratified by sex or parity are not available, adjustments should be made. In multinational studies, comparisons should be made between results using both a common standard and country-based standards.

Item Type:	Journal Article
Subjects:	R Medicine > RJ Pediatrics
Divisions:	Faculty of Science, Engineering and Medicine > Science > Statistics
Library of Congress Subject Headings (LCSH):	Birth weight, Low -- Europe, Birth weight, Low -- Standards, Gestational age -- Testing, Medicine -- Statistical methods, Medicine, Comparative -- Europe
Journal or Publication Title:	Developmental Medicine and Child Neurology
Publisher:	Cambridge University Press
ISSN:	0012-1622
Official Date:	November 2006
Dates:	Date Event November 2006 Published
Volume:	Vol.48
Number:	No.11
Page Range:	pp. 906-912
DOI:	10.1017/S0012162206001988
Status:	Peer Reviewed
Access rights to Published version:	Open Access (Creative Commons)
Funder:	Medical Research Council (Great Britain) (MRC), European Commission (EC)
Grant number:	DGXIIBIOMED2- Contract NBMH4-983701 (EC)

Data sourced from Thomson Reuters' Web of Knowledge

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