Gates, Simon, Quinn, Tom, Deakin, Charles D., Blair, Laura, Couper, Keith and Perkins, Gavin D. (2015) Mechanical chest compression for out of hospital cardiac arrest : systematic review and meta-analysis. Resuscitation, 94 . pp. 91-97. doi:10.1016/j.resuscitation.2015.07.002

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Abstract

Aim:
To summarise the evidence from randomised controlled trials of mechanical chest compression devices used during resuscitation after out of hospital cardiac arrest.

Methods:
Systematic review of studies evaluating the effectiveness of mechanical chest compression. We included randomised controlled trials or cluster randomised trials that compared mechanical chest compression (using any device) with manual chest compression for adult patients following out-of-hospital cardiac arrest. Outcome measures were return of spontaneous circulation, survival of event, overall survival, survival with good neurological outcome. Results were combined using random-effects meta-analysis.

Data sources:
Studies were identified by searches of electronic databases, reference lists of other studies and review articles.

Results:
Five trials were included, of which three evaluated the LUCAS or LUCAS-2 device and two evaluated the AutoPulse device. The results did not show an advantage to the use of mechanical chest compression devices for survival to discharge/30 days (average OR 0.89, 95% CI 0.77, 1.02) and survival with good neurological outcome (average OR 0.76, 95% CI 0.53, 1.11).

Conclusions:
Existing studies do not suggest that mechanical chest compression devices are superior to manual chest compression, when used during resuscitation after out of hospital cardiac arrest.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences > Clinical Trials Unit Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	CPR (First aid), Cardiac arrest
Journal or Publication Title:	Resuscitation
Publisher:	Elsevier Ireland Ltd
ISSN:	0300-9572
Official Date:	September 2015
Dates:	Date Event September 2015 Published 17 July 2015 Available 10 July 2015 Accepted 9 April 2015 Submitted
Date of first compliant deposit:	30 December 2015
Volume:	94
Number of Pages:	7
Page Range:	pp. 91-97
DOI:	10.1016/j.resuscitation.2015.07.002
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Funder:	National Institute for Health Research (Great Britain) (NIHR)
Grant number:	07/37/69 (NIHR)
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