Ribosome-inactivating proteins: Entry into mammalian cells and intracellular routing
UNSPECIFIED (2004) Ribosome-inactivating proteins: Entry into mammalian cells and intracellular routing. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 4 (5). pp. 505-512. ISSN 1389-5575Full text not available from this repository.
To catalytically-modify ribosomes in vivo, ribosome-inactivating proteins produced by plants must enter susceptible mammalian cells in order to reach their substrates in the cytosol. This review primarily focuses on the biosynthesis, mechanism of cell entry and intracellular trafficking of ricin, the most thoroughly studied ribosome-inactivating protein in this respect.
|Item Type:||Journal Item|
|Subjects:||Q Science > QD Chemistry|
|Journal or Publication Title:||MINI-REVIEWS IN MEDICINAL CHEMISTRY|
|Publisher:||BENTHAM SCIENCE PUBL LTD|
|Official Date:||June 2004|
|Number of Pages:||8|
|Page Range:||pp. 505-512|
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