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Economic costs associated with moderate and late preterm birth : a prospective population-based study
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Khan, K. A., Petrou, Stavros, Dritsaki, Melina, Johnson, S. J., Manktelow, B., Draper, E. S., Smith, L. K., Seaton, S. E , Marlow, N., Dorling, J., Field, D. J. and Boyle, E. M. (2015) Economic costs associated with moderate and late preterm birth : a prospective population-based study. BJOG : An International Journal of Obstetrics & Gynaecology, 122 (11). pp. 1495-1505. doi:10.1111/1471-0528.13515 ISSN 1470-0328.
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Official URL: http://dx.doi.org/10.1111/1471-0528.13515
Abstract
Objective
We sought to determine the economic costs associated with moderate and late preterm birth.
Design
An economic study was nested within a prospective cohort study.
Sample
Infants born between 32+0 and 36+6 weeks of gestation in the East Midlands of England. A sample of infants born at ≥37 weeks of gestation acted as controls.
Methods
Data on resource use, estimated from a National Health Service (NHS) and personal social services perspective, and separately from a societal perspective, were collected between birth and 24 months corrected age (or death), and valued in pounds sterling, at 2010–11 prices. Descriptive statistics and multivariable analyses were used to estimate the relationship between gestational age at birth and economic costs.
Main outcome measures
Cumulative resource use and economic costs over the first two years of life.
Results
Of all eligible births, 1146 (83%) preterm and 1258 (79%) term infants were recruited. Mean (standard error) total societal costs from birth to 24 months were £12 037 (£1114) and £5823 (£1232) for children born moderately preterm (32+0–33+6 weeks of gestation) and late preterm (34+0–36+6 weeks of gestation), respectively, compared with £2056 (£132) for children born at term. The mean societal cost difference between moderate and late preterm and term infants was £4657 (bootstrap 95% confidence interval, 95% CI £2513–6803; P < 0.001). Multivariable regressions revealed that, after controlling for clinical and sociodemographic characteristics, moderate and late preterm birth increased societal costs by £7583 (£874) and £1963 (£337), respectively, compared with birth at full term.
Conclusions
Moderate and late preterm birth is associated with significantly increased economic costs over the first 2 years of life. Our economic estimates can be used to inform budgetary and service planning by clinical decision-makers, and economic evaluations of interventions aimed at preventing moderate and late preterm birth or alleviating its adverse consequences.
Item Type: | Journal Article | ||||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | BJOG : An International Journal of Obstetrics & Gynaecology | ||||||||
Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||||
ISSN: | 1470-0328 | ||||||||
Official Date: | October 2015 | ||||||||
Dates: |
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Volume: | 122 | ||||||||
Number: | 11 | ||||||||
Page Range: | pp. 1495-1505 | ||||||||
DOI: | 10.1111/1471-0528.13515 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Access rights to Published version: | Restricted or Subscription Access |
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