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SurgiCal obesity treatment study (SCOTS) : protocol for a national prospective cohort study of patients undergoing bariatric surgery in Scotland

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Logue, Jennifer, Stewart, Sally, Munro, Jane, Bruce, J. (Julie), Grieve, Eleanor, Lean, M. E. J. (Michael Ernest John), Lindsay, Robert S., Bruce, Duff M., Ali, Abdulmajid, Briggs, Andrew H., Sattar, Naveed and Ford, Ian (2015) SurgiCal obesity treatment study (SCOTS) : protocol for a national prospective cohort study of patients undergoing bariatric surgery in Scotland. BMJ Open, 5 (5). pp. 1-8. e008106. doi:10.1136/bmjopen-2015-008106 ISSN 2044-6055.

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Official URL: http://dx.doi.org/10.1136/bmjopen-2015-008106

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Abstract

Introduction: The efficacy of bariatric surgery for large-scale, long-term weight loss is well established. However, many questions remain over the continual benefits and cost-effectiveness of that weight loss for overall health, particularly when accounting for potential complications and adverse events of surgery. Health research institutes in the UK and the USA have called for high-quality longitudinal cohort studies of patients undergoing bariatric surgery, assessing outcomes such as surgical complications, mortality, diabetes remission, microvascular complications, cardiovascular events, mental health, cost and healthcare use.

Methods and analysis: SurgiCal Obesity Treatment Study (SCOTS) is a national, prospective, observational, cohort study of patients undergoing primary bariatric surgical procedures in Scotland. This study aims to recruit 2000 patients and conduct a follow-up for 10 years postbariatric surgery using multiple data collection methods: surgeon-recorded data, electronic health record linkage, and patient-reported outcome measures. Outcomes measured will include: mortality, weight change, diabetes, surgical, cardiovascular, cancer, behavioural, reproductive/urological and nutritional variables. Healthcare utilisation and economic productivity will be collected to inform cost-effectiveness analysis.

Ethics and dissemination: The study has received a favourable ethical opinion from the West of Scotland Research Ethics committee. All publications arising from this cohort study will be published in open-access peer-reviewed journals. All SCOTS investigators (all members of the research team at every recruiting site) will have the ability to propose research suggestions and potential publications using SCOTS data; a publications committee will approve all requests for use of SCOTS data and propose writing committees and timelines. Lay-person summaries of all research findings will be published simultaneously on the SCOTS website (http://www.scotsurgeystudy.org.uk).

Item Type: Journal Article
Subjects: R Medicine > RC Internal medicine
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Obesity -- Surgery
Journal or Publication Title: BMJ Open
Publisher: BMJ
ISSN: 2044-6055
Official Date: 22 May 2015
Dates:
DateEvent
22 May 2015Published
14 April 2015Accepted
4 April 2015Submitted
Volume: 5
Number: 5
Number of Pages: 8
Page Range: pp. 1-8
Article Number: e008106
DOI: 10.1136/bmjopen-2015-008106
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 31 December 2015
Date of first compliant Open Access: 31 December 2015
Funder: NIHR Health Technology Assessment Programme (Great Britain)
Grant number: 10/42/02 (NIHR)
Adapted As:
Contributors:
ContributionNameContributor ID
Research GroupSurgiCal Obesity Treatment Study (SCOTS) Investigators, UNSPECIFIED

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