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Comment on "The Dynamic Control of Kiss-and-Run and Vesicular Reuse Probed with Single Nanoparticles"
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Granseth, B., Odermatt, B., Royle, Stephen J. and Lagnado, L. (2009) Comment on "The Dynamic Control of Kiss-and-Run and Vesicular Reuse Probed with Single Nanoparticles". Science, 325 (5947). p. 1499. doi:10.1126/science.1175790 ISSN 0036-8075.
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Official URL: http://dx.doi.org/10.1126/science.1175790
Abstract
Zhang et al. (Research Articles, 13 March 2009, p. 1448) reported that synaptic vesicles usually release neurotransmitter through a kiss-and-run mechanism occurring within 1 second but that full collapse of the vesicles becomes more prevalent with repeated stimuli. We report that the kinetics of vesicle retrieval do not change during a stimulus train, with endocytosis occurring in 10 to 15 seconds.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Cell & Developmental Biology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Science | ||||
Publisher: | American Association for the Advancement of Science | ||||
ISSN: | 0036-8075 | ||||
Official Date: | September 2009 | ||||
Dates: |
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Volume: | 325 | ||||
Number: | 5947 | ||||
Page Range: | p. 1499 | ||||
DOI: | 10.1126/science.1175790 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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