
The Library
The clinical use of platelet-rich plasma in the promotion of bone healing : a systematic review
Tools
Griffin, Xavier L., Smith, C. M. and Costa, Matthew L. (2009) The clinical use of platelet-rich plasma in the promotion of bone healing : a systematic review. Injury, 40 (2). pp. 158-162. doi:10.1016/j.injury.2008.06.025 ISSN 0020-1383.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.injury.2008.06.025
Abstract
Platelet-rich plasma has been shown in several in vitro and animal studies to play a role in promoting new bone formation. A systematic literature review was conducted to identify the current relevant evidence base, searching across multiple sources including Medline, Embase and the Cochrane Library, and finding five clinically relevant articles. Only one was a randomised controlled trial, but this was underpowered for the outcome measure defined. Three studies exclusively concerned children, and included those with congenital limb deformities. Two other reports were case series. Early clinical results suggest that the use of platelet-rich plasma is safe and feasible, but that at present there is no clinical evidence of benefit in either acute or delayed fracture healing.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Journal or Publication Title: | Injury | ||||
Publisher: | Elsevier | ||||
ISSN: | 0020-1383 | ||||
Official Date: | 2009 | ||||
Dates: |
|
||||
Volume: | 40 | ||||
Number: | 2 | ||||
Page Range: | pp. 158-162 | ||||
DOI: | 10.1016/j.injury.2008.06.025 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
![]() |
View Item |