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Schizophrenia postdrome : a study of low-level psychotic experience after remission of first-episode schizophrenia
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Burley, Kate, Upthegrove, Rachel, Birchwood, M. J., Patterson, Paul and Skeate, Amanda (2009) Schizophrenia postdrome : a study of low-level psychotic experience after remission of first-episode schizophrenia. Early Intervention in Psychiatry, 3 (4). pp. 296-299. doi:10.1111/j.1751-7893.2009.00141.x ISSN 1751-7885.
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Official URL: http://dx.doi.org/10.1111/j.1751-7893.2009.00141.x
Abstract
Background: Despite remission being the primary objective following the first episode of schizophrenia, clinically stabilized patients nevertheless relapse.
Aim: To assess the extent and fluctuation of low-level psychotic symptoms in patients who are in remission after first-episode schizophrenia and consider whether this is equivalent to symptomatology experienced by those at ‘ultra high risk’ (UHR) of developing first-episode psychosis.
Methods: We examined the phenomenological characteristics of 11 patients who fulfilled international remission criteria using the Structured Interview for Prodromal Symptoms and compared this cohort with an UHR sample.
Results: Remitted patients were experiencing attenuated positive symptoms (73%) and brief limited intermittent psychotic symptoms (18%), features that were similarly prevalent in the UHR group. There was no significant fluctuation in these low-level symptoms over the course of four interviews.
Conclusions: Although further research is required in this novel field, such features could form the building blocks for better prediction of psychotic relapse.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
Journal or Publication Title: | Early Intervention in Psychiatry | ||||
Publisher: | Wiley-Blackwell Publishing Ltd. | ||||
ISSN: | 1751-7885 | ||||
Official Date: | 2009 | ||||
Dates: |
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Volume: | 3 | ||||
Number: | 4 | ||||
Page Range: | pp. 296-299 | ||||
DOI: | 10.1111/j.1751-7893.2009.00141.x | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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