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Schizophrenia postdrome : a study of low-level psychotic experience after remission of first-episode schizophrenia

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Burley, Kate, Upthegrove, Rachel, Birchwood, M. J., Patterson, Paul and Skeate, Amanda (2009) Schizophrenia postdrome : a study of low-level psychotic experience after remission of first-episode schizophrenia. Early Intervention in Psychiatry, 3 (4). pp. 296-299. doi:10.1111/j.1751-7893.2009.00141.x ISSN 1751-7885.

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Official URL: http://dx.doi.org/10.1111/j.1751-7893.2009.00141.x

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Abstract

Background: Despite remission being the primary objective following the first episode of schizophrenia, clinically stabilized patients nevertheless relapse.

Aim: To assess the extent and fluctuation of low-level psychotic symptoms in patients who are in remission after first-episode schizophrenia and consider whether this is equivalent to symptomatology experienced by those at ‘ultra high risk’ (UHR) of developing first-episode psychosis.

Methods: We examined the phenomenological characteristics of 11 patients who fulfilled international remission criteria using the Structured Interview for Prodromal Symptoms and compared this cohort with an UHR sample.

Results: Remitted patients were experiencing attenuated positive symptoms (73%) and brief limited intermittent psychotic symptoms (18%), features that were similarly prevalent in the UHR group. There was no significant fluctuation in these low-level symptoms over the course of four interviews.

Conclusions: Although further research is required in this novel field, such features could form the building blocks for better prediction of psychotic relapse.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title: Early Intervention in Psychiatry
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 1751-7885
Official Date: 2009
Dates:
DateEvent
2009Published
Volume: 3
Number: 4
Page Range: pp. 296-299
DOI: 10.1111/j.1751-7893.2009.00141.x
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

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