The Library
Ultrasound elastography as an adjuvant to conventional ultrasound in the preoperative assessment of axillary lymph nodes in suspected breast cancer : a pilot study
Tools
Taylor, K., O’Keeffe, S., Britton, P. D., Wallis, M. G., Treece, G. M., Housden, J., Parashar, D., Bond, S. and Sinnatamby, R. (2011) Ultrasound elastography as an adjuvant to conventional ultrasound in the preoperative assessment of axillary lymph nodes in suspected breast cancer : a pilot study. Clinical Radiology, 66 (11). pp. 1064-1071. S0009-9260(11)00241-8. doi:10.1016/j.crad.2011.05.015 ISSN 0009-9260.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.crad.2011.05.015
Abstract
AIMS:
To compare the performance of ultrasound elastography with conventional ultrasound in the assessment of axillary lymph nodes in suspected breast cancer and whether ultrasound elastography as an adjunct to conventional ultrasound can increase the sensitivity of conventional ultrasound used alone.
MATERIALS AND METHODS:
Fifty symptomatic women with a sonographic suspicion for breast cancer underwent ultrasound elastography of the ipsilateral axilla concurrent with conventional ultrasound being performed as part of triple assessment. Elastograms were visually scored, strain measurements calculated and node area and perimeter measurements taken. Theoretical biopsy cut points were selected. The sensitivity, specificity, positive predictive value (PPV), and negative predictive values (NPV) were calculated and receiver operating characteristic (ROC) analysis was performed and compared for elastograms and conventional ultrasound images with surgical histology as the reference standard.
RESULTS:
The mean age of the women was 57 years. Twenty-nine out of 50 of the nodes were histologically negative on surgical histology and 21 were positive. The sensitivity, specificity, PPV, and NPV for conventional ultrasound were 76, 78, 70, and 81%, respectively; 90, 86, 83, and 93%, respectively, for visual ultrasound elastography; and for strain scoring, 100, 48, 58 and 100%, respectively. There was no significant difference between any of the node measurements
CONCLUSIONS:
Initial experience with ultrasound elastography of axillary lymph nodes, showed that it is more sensitive than conventional ultrasound in detecting abnormal nodes in the axilla in cases of suspected breast cancer. The specificity remained acceptable and ultrasound elastography used as an adjunct to conventional ultrasound has the potential to improve the performance of conventional ultrasound alone
Item Type: | Journal Article | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Cancer Research Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||||||||
Journal or Publication Title: | Clinical Radiology | ||||||||||
Publisher: | W.B. Saunders Co. Ltd. | ||||||||||
ISSN: | 0009-9260 | ||||||||||
Official Date: | November 2011 | ||||||||||
Dates: |
|
||||||||||
Volume: | 66 | ||||||||||
Number: | 11 | ||||||||||
Page Range: | pp. 1064-1071 | ||||||||||
Article Number: | S0009-9260(11)00241-8 | ||||||||||
DOI: | 10.1016/j.crad.2011.05.015 | ||||||||||
Status: | Peer Reviewed | ||||||||||
Publication Status: | Published | ||||||||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |