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Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group
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Bechdolf, A., Thompson, Andrew D., Nelson, B., Cotton, S., Simmons, M. B., Amminger, G. P., Leicester, S., Francey, S. M., McNab, C., Krstev, H., Sidis, A., McGorry, P. D. and Yung, A. R. (2010) Experience of trauma and conversion to psychosis in an ultra-high-risk (prodromal) group. Acta Psychiatrica Scandinavica, 121 (5). pp. 377-384. doi:10.1111/j.1600-0447.2010.01542.x ISSN 0001-690X.
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Official URL: http://dx.doi.org/10.1111/j.1600-0447.2010.01542.x
Abstract
Objective: We aimed to replicate a recent finding of high prevalence of trauma history in patients at ‘ultra-high risk’ (UHR) of psychotic disorder and to investigate whether trauma predicts conversion to psychosis in this population.
Method: A consecutive sample of UHR patients was assessed. History of trauma was accessed with the General Trauma Questionnaire. Cox regression models were used to explore relationship between conversion to psychosis and trauma.
Results: Of 92 UHR patients nearly 70% had experienced a traumatic event and 21.7% developed psychosis during follow-up (mean 615 days). Patients who had experienced a sexual trauma (36%) were significantly more likely to convert to first-episode psychosis (OR 2.96) after controlling for meeting multiple UHR intake groups.
Conclusion: UHR patients have a high prevalence of history of trauma. Previous sexual trauma may be a predictor of onset of psychotic disorder in this population.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Acta Psychiatrica Scandinavica | ||||
| Publisher: | Wiley-Blackwell Publishing, Inc. | ||||
| ISSN: | 0001-690X | ||||
| Official Date: | 2010 | ||||
| Dates: |
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| Volume: | 121 | ||||
| Number: | 5 | ||||
| Page Range: | pp. 377-384 | ||||
| DOI: | 10.1111/j.1600-0447.2010.01542.x | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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